Evidence map›Paper›PMID 39893295›Full record

ArticleScientific reports2025

Integrative computational analysis of anti-influenza potential in Caesalpinia mimosoides Lamk hydroethanolic extract.

Anuwatchakij Klamrak, Shaikh Shahinur Rahman, Napapuch Nopkuesuk, Jaran Nabnueangsap, Jaraspim Narkpuk, Piyapon Janpan, Yutthakan Saengkun, Thananya Soonkum, Supawadee Sriburin, Samaporn Teeravechyan and 8 more

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Anuwatchakij Klamrak *Division of Pharmacognosy and Toxicology, Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen, 40002, Thailand.
Shaikh Shahinur Rahman *Division of Pharmacognosy and Toxicology, Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen, 40002, Thailand.
Napapuch NopkuesukDivision of Pharmacognosy and Toxicology, Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen, 40002, Thailand.
Jaran NabnueangsapSalaya Central Instrument Faculty RSPG, Research Management and Development Division, Mahidol University, Bangkok, Thailand.
Jaraspim NarkpukVirology and Cell Technology Research Team, National Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency (NSTDA), Pathumthani, 12120, Thailand.
Piyapon JanpanDivision of Pharmacognosy and Toxicology, Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen, 40002, Thailand.
Yutthakan SaengkunDivision of Pharmacognosy and Toxicology, Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen, 40002, Thailand.
Thananya SoonkumSalaya Central Instrument Faculty RSPG, Research Management and Development Division, Mahidol University, Bangkok, Thailand.
Supawadee SriburinDivision of Pharmacognosy and Toxicology, Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen, 40002, Thailand.
Samaporn TeeravechyanVirology and Cell Technology Research Team, National Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency (NSTDA), Pathumthani, 12120, Thailand.
Poramet SitthiwongKhaoyai Panorama Farm Co., Ltd, 297 M.6, Thanarat Rd., Nongnamdang, Pakchong, Nakhonratchasima, 30130, Thailand.
Nisachon JangprommaProtein and Proteomics Research Center for Commercial and Industrial Purposes (ProCCI), Khon Kaen University, Khon Kaen, 40002, Thailand.
Sirinan KulchatDepartment of Chemistry, Faculty of Science, Khon Kaen University, Khon Kaen, 40002, Thailand.
Kiattawee ChoowongkomonDepartment of Biochemistry, Faculty of Sciences, Kasetsart University, Bangkok, Thailand.
Rina PatramanonProtein and Proteomics Research Center for Commercial and Industrial Purposes (ProCCI), Khon Kaen University, Khon Kaen, 40002, Thailand.
Arunrat ChaveerachDepartment of Biology, Faculty of Science, Khon Kaen University, Khon Kaen, 40002, Thailand.
Jureerut DaduangDepartment of Clinical Chemistry, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen, 40002, Thailand.
Sakda DaduangDivision of Pharmacognosy and Toxicology, Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen, 40002, Thailand. sakdad@kku.ac.th.

Funding

Program Management Unit for Human Resources and Institutional Development, Research and Innovation (PMU-B) B13F660069
6 · The paper itself

Abstract

In a recent study, we used chemical analysis to show that the Caesalpinia mimosoides aqueous extract, which contains a high concentration of simple phenolics, has strong anti-influenza activity. We determined through molecular docking methods that its potential target inhibitor is the neuraminidase. Therefore, our study objectives were to evaluate whether the aqueous-ethanol extract (30% v/v) of this plant species exhibits greater antiviral activity than the aqueous plant extract. The C. mimosoides hydroethanolic extract exhibited potent antioxidant activity in the DPPH assay, with an IC

Indexed as

Antiviral AgentsCaesalpiniaPlant ExtractsAnimalsAntioxidantsEthanolHumansMolecular Docking SimulationNeuraminidasePhenolsAntioxidantsAntiviral AgentsEthanolNeuraminidasePhenolsPlant ExtractsAnti-influenzaCaesalpinia mimosoides LamkCheminformaticsHydroethanolic extractMolecular dockingPhytochemical profiling

Identifiers

PMID39893295
PMCPMC11787316

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.