ArticleGlobal heart2025
Evaluating the World Health Organization's Hearts Model for Hypertension and Diabetes Management: A Pilot Implementation Study in Guatemala.
Article in Global heart, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06080451 (Implementing Integrated Diabetes and Hypertension Management in Guatemala Using the HEARTS Model), which is not on this map. Cited by 10 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Implementing Integrated Diabetes and Hypertension Management in Guatemala Using the HEARTS Model
Who cites it
10 citing papers in PubMed.
- Scaling integrated cardiovascular-kidney-metabolic care through primary health care in the Americas: a health policy analysis of HEARTS 2.0 implementation levers and architecture.Lancet regional health. Americas · 2026Review
- Adoption, implementation, and evaluation of the HEARTS initiative on blood pressure outcomes: a quality improvement project in a large healthcare system in the United States.Lancet regional health. Americas · 2026Article
- Evaluating implementation of the HEARTS model for management of hypertension and diabetes in Guatemala: protocol for a prospective observational hybrid type 3 study.Implementation science communications · 2026Article
- Implementation of stroke prevention: a review of challenges and opportunities in the Americas.Lancet regional health. Americas · 2026Review
- Understanding implementation of HEARTS for hypertension and diabetes in Guatemala: Qualitative and mixed-methods pilot results.medRxiv : the preprint server for health sciences · 2026Article
- Readiness to deliver integrated cardiovascular, kidney and metabolic care in primary healthcare: phase II of HEARTS 2.0 in 26 countries in the Americas.BMJ global health · 2026Article
- HEARTS quality: a policy framework to strengthen hypertension and cardiovascular risk management in primary healthcare-insights from HEARTS in the Americas.Lancet regional health. Americas · 2026Review
- Prevalence, awareness, treatment and control of diabetes in Guatemala: a nationally representative survey among reproductive-age women.BMJ public health · 2026Article
- [HEARTS quality: a policy framework to strengthen hypertension and cardiovascular risk management in primary healthcare - insights from HEARTS in the AmericasQualidade da iniciativa HEARTS: marco de políticas para fortalecer o manejo da hipertensão e do risco cardiovascular na atenção primária à saúde. Perspectivas da iniciativa HEARTS nas Américas].Revista panamericana de salud publica = Pan American journal of public health · 2026Article
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11 authors.
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Abstract
Background: The World Health Organization HEARTS Technical Package is a widely implemented global initiative to improve the primary care management of cardiovascular disease risk factors. The study's objective is to report outcomes from a pilot implementation trial of integrated hypertension and diabetes management based on the HEARTS model in Guatemala. Methods: We conducted a single-arm pilot implementation trial over six months from October 2023 to May 2024 in 11 Guatemalan Ministry of Health primary care facilities in two districts. The pilot evaluated a package of five HEARTS-aligned implementation strategies to improve the pharmacological treatment of hypertension and diabetes. The primary outcomes were feasibility and acceptability, measured through 20 structured interviews with Ministry of Health employees and by examining enrolment and retention data. Secondary outcomes included a suite of implementation and clinical outcomes, including treatment rates. When baseline data were available, we analyzed secondary outcomes as the net change from baseline or using an interrupted time series approach. Results: The study enrolled 964 patients, of whom 58.8% had hypertension only, 30.4% had diabetes only, and 10.8% had both conditions. Surveys on feasibility and acceptability among Ministry of Health staff had a median score of 5.0 (IQR: 5.0 to 5.0) and 5.0 (IQR range: 4.8 to 5.0), respectively, exceeding the prespecified benchmark of ≥3.5. Both districts achieved the prespecified benchmark of enrolling ≥25 hypertension patients and ≥25 diabetes patients. Only 36% of patients attended a follow-up visit within three months, lower than the prespecified benchmark of ≥75%. Monthly treatment rates during the pilot increased by 22.3 (95% CI: 16.2 to 28.4; P < 0.001) and 3.5 (95% CI: -1.6 to 8.7; P = 0.17) patients per month for hypertension and diabetes, respectively. Conclusions: Implementation of an integrated hypertension and diabetes model based on HEARTS was generally feasible and acceptable in the Ministry of Health in Guatemala. Findings can refine national scale-up in Guatemala and inform HEARTS implementation projects in other settings.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.