Evidence mapPaperPMID 39897018Full record

ArticlePostepy w kardiologii interwencyjnej = Advances in interventional cardiology2024

Plasma leukocyte-derived extracellular vesicles are related to target vessel revascularization in off-pump coronary artery bypass grafting.

Tomasz K Urbanowicz, Aleksandra Gąsecka, Anna Olasińska-Wiśniewska, Michał Michalak, Michał Rodzki, Ewelina Błażejowska, Krzysztof J Filipiak, Mariusz Kowalewski, Andrzej Tykarski, Marek Jemielity

Abstract read
In one paragraph

Article in Postepy w kardiologii interwencyjnej = Advances in interventional cardiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. How Advanced Is Nanomedicine for Atherosclerosis?International journal of nanomedicine · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tomasz K UrbanowiczCardiac Surgery and Transplantology Department, Poznan University of Medical Sciences, Poznan, Poland.
Aleksandra Gąsecka1 Chair and Department of Cardiology, Medical University of Warsaw, Warsaw, Poland.
Anna Olasińska-WiśniewskaCardiac Surgery and Transplantology Department, Poznan University of Medical Sciences, Poznan, Poland.
Michał MichalakDepartment of Computer Science and Statistics, Poznan University of Medical Sciences, Poznan, Poland.
Michał RodzkiCardiac Surgery and Transplantology Department, Poznan University of Medical Sciences, Poznan, Poland.
Ewelina Błażejowska1 Chair and Department of Cardiology, Medical University of Warsaw, Warsaw, Poland.
Krzysztof J FilipiakMaria Sklodowska-Curie Medical Academy, Warsaw, Poland.
Mariusz KowalewskiDepartment of Cardiac Surgery, Center of Postgraduate Medical Education, Central Clinical Hospital of the Ministry of Interior, Warsaw, Poland.
Andrzej TykarskiDepartment of Hypertensiology, Angiology and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland.
Marek JemielityCardiac Surgery and Transplantology Department, Poznan University of Medical Sciences, Poznan, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: In multivessel coronary disease, interventional therapy is recommended to improve symptoms and survival. Inflammatory activation is postulated as one of the coronary atherosclerosis progression risk factors and prognostic indicators of surgical intervention. Counts of plasma extracellular vesicles (EVs) derived from erythrocytes, leukocytes, and platelets are elevated in patients with inflammatory diseases, including atherosclerosis-based cardiovascular diseases. Aim: We aimed to estimate the association between blood flow measurements in coronary artery bypass grafts and EV plasma count changes in patients undergoing surgical coronary revascularization. Material and methods: Forty-four consecutive patients who underwent surgical off-pump revascularization (33 males, 75%) in the median (Q1-Q3) age of 65 (58-69) were included. The blood flow in the implanted coronary artery bypass grafts was measured intraoperatively. EV counts were measured at baseline (hospital admission) and on the 1 Results: The numbers of leukocyte-derived EVs were lower in patients who received a LIMA-LAD graft ( Conclusions: Surgical revascularizations affect EV plasma count, including significantly lower postoperative values of leukocyte-derived EVs related to left descending artery grafting.

Indexed as

CD235CD45CD61extracellular vesiclesleft descending arteryoff-pump coronary artery bypass grafting

Identifiers

PMID39897018
PMCPMC11783267

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.