Evidence map›Paper›PMID 39899166›Full record

ArticleBiochemical genetics2026

Association of HindIII Polymorphism of the Lipoprotein Lipase (LPL) Gene (rs320) and Plasma Metabolic Parameters in a Nigerian Population.

Joseph O Faleti, Holiness S A Olasore, Matthew O Olawale, Abdullahi A Murtala, Taiwo O Banjo, Miriam N Igwo-Ezikpe

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Article in Biochemical genetics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Joseph O FaletiDepartment of Biochemistry, College of Medicine, University of Lagos, Idi-Araba Campus, Surulere, Lagos State, Nigeria.
Holiness S A OlasoreDepartment of Biochemistry, College of Medicine, University of Lagos, Idi-Araba Campus, Surulere, Lagos State, Nigeria. holashore@unilag.edu.ng.ORCID http://orcid.org/0000-0003-3082-3203
Matthew O OlawaleDepartment of Biochemistry, College of Medicine, University of Lagos, Idi-Araba Campus, Surulere, Lagos State, Nigeria.
Abdullahi A MurtalaDepartment of Pharmacology and Therapeutics, Obafemi Awolowo College of Health Sciences, Olabisi Onabanjo University, Sagamu Campus, Sagamu, Ogun State, Nigeria.
Taiwo O BanjoDepartment of Medical Microbiology and Parasitology, Obafemi Awolowo College of Health Sciences, Olabisi Onabanjo University, Sagamu Campus, Sagamu, Ogun State, Nigeria.
Miriam N Igwo-EzikpeDepartment of Biochemistry, College of Medicine, University of Lagos, Idi-Araba Campus, Surulere, Lagos State, Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genetic variations in the lipoprotein lipase (LPL) gene including the HindIII polymorphism (rs320) have been reported to modify fat metabolism, adiposity, and body weight. However, little attention has been given to the African population. The present study aimed to investigate the relationship between the rs320 gene polymorphism and a number of metabolic and anthropometric parameters in a sample of the Nigerian population. We recruited 236 participants for the study. The participants were required to sign informed consent forms after which information related to their calorie intake and utilization as well as anthropometric measurements were recorded. Plasma metabolic parameters were subsequently determined using an autoanalyzer. Genotyping for HindIII polymorphism was performed using the PCR-RFLP method. The frequencies (n) of T and G alleles were 0.841 (397) and 0.158 (75), while the frequencies (n) of TT, TG, and GG were 0.691(163), 0.301(71), and 0.01(2), respectively. The population was not in Hardy-Weinberg equilibrium (χ

Indexed as

Lipoprotein LipasePolymorphism, Single NucleotideAdultBlood GlucoseFemaleGene FrequencyGenotypeHumansMaleMiddle AgedNigeriaBlood GlucoseLipoprotein LipaseLPL protein, humanGeneticsLipid metabolismLipoprotein lipaseRFLPWeight gain

Identifiers

PMID39899166

What Socratic holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.