Evidence map›Paper›PMID 39901025›Full record

ArticleCommunications biology2025

Prolonged exposure to heat enhances mosquito tolerance to viral infection.

Hugo D Perdomo, Ayda Khorramnejad, Nfamara M Cham, Alida Kropf, Davide Sogliani, Mariangela Bonizzoni

Abstract read
In one paragraph

Article in Communications biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hugo D Perdomo *Department of Biology and Biotechnology, University of Pavia, via Ferrata 9, 27100, Pavia, Italy.ORCID http://orcid.org/0000-0002-8783-1557
Ayda Khorramnejad *Department of Biology and Biotechnology, University of Pavia, via Ferrata 9, 27100, Pavia, Italy.ORCID http://orcid.org/0000-0003-1110-5791
Nfamara M ChamDepartment of Biology and Biotechnology, University of Pavia, via Ferrata 9, 27100, Pavia, Italy.ORCID http://orcid.org/0009-0005-1946-9997
Alida KropfDepartment of Biology and Biotechnology, University of Pavia, via Ferrata 9, 27100, Pavia, Italy.
Davide SoglianiDepartment of Biology and Biotechnology, University of Pavia, via Ferrata 9, 27100, Pavia, Italy.
Mariangela BonizzoniDepartment of Biology and Biotechnology, University of Pavia, via Ferrata 9, 27100, Pavia, Italy. m.bonizzoni@unipv.it.ORCID http://orcid.org/0000-0003-0568-8564

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

How and to what extent mosquito-virus interaction is influenced by climate change is a complex question of ecological and epidemiological relevance. We worked at the intersection between thermal biology and vector immunology and studied shifts in tolerance and resistance to the cell fusing agent virus (CFAV), a prominent component of the mosquito virome known to contribute to shaping mosquito vector competence, in warm-acclimated and warm-evolved Aedes albopictus mosquitoes. We show that the length of the thermal challenge influences the outcome of the infection with warm-evolved mosquitoes being more tolerant to CFAV infection, while warm-acclimated mosquitoes being more resistant and suffering from extensive fitness costs. These results highlight the importance of considering fluctuations in vector immunity in relation to the length of a thermal challenge to understand natural variation in vector response to viruses and frame realistic transmission models.

Indexed as

AedesHot TemperatureMosquito VectorsAnimalsClimate ChangeFemale

Identifiers

PMID39901025
PMCPMC11790978

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.