Evidence map›Paper›PMID 39901187›Full record

ArticleBMC medical informatics and decision making2025

Accounting for racial bias and social determinants of health in a model of hypertension control.

Yang Hu, Nicholas Cordella, Rebecca G Mishuris, Ioannis Ch Paschalidis

Abstract read
In one paragraph

Article in BMC medical informatics and decision making, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yang HuDepartment of Electrical and Computer Engineering, Department of Biomedical Engineering, Division of Systems Engineering, and Faculty of Computing & Data Sciences, Boston University, 8 Saint Mary's St., Boston, MA, 02215, USA.
Nicholas CordellaDepartment of Medicine, Boston Medical Center and Boston University School of Medicine, Boston, MA, USA.
Rebecca G MishurisMass General Brigham and Harvard Medical School, Boston, MA, USA.
Ioannis Ch PaschalidisDepartment of Electrical and Computer Engineering, Department of Biomedical Engineering, Division of Systems Engineering, and Faculty of Computing & Data Sciences, Boston University, 8 Saint Mary's St., Boston, MA, 02215, USA. yannisp@bu.edu.

Funding

Optimizing and Learning Strategies for Protein Docking R01GM135930 · NIGMS · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI VAKILI, PIROOZ · 2019 to 2021
$561k
Boston University Clinical and Translational Science Award (CTSA) UL54 TR004130National Science Foundation IIS-1914792NIGMS NIH HHS R01 GM135930NIH HHS R01 GM135930Office of Naval Research N00014-19-1-2571
6 · The paper itself

Abstract

backgroundHypertension control remains a critical problem and most of the existing literature views it from a clinical perspective, overlooking the role of sociodemographic factors. This study aims to identify patients with not well-controlled hypertension using readily available demographic and socioeconomic features and elucidate important predictive variables.

methodsIn this retrospective cohort study, records from 1/1/2012 to 1/1/2020 at the Boston Medical Center were used. Patients with either a hypertension diagnosis or related records (≥ 130 mmHg systolic or ≥ 90 mmHg diastolic, n = 164,041) were selected. Models were developed to predict which patients had uncontrolled hypertension defined as systolic blood pressure (SBP) records exceeding 160 mmHg.

resultsThe predictive model of high SBP reached an Area Under the Receiver Operating Characteristic Curve of 74.49% ± 0.23%. Age, race, Social Determinants of Health (SDoH), mental health, and cigarette use were predictive of high SBP. Being Black or having critical social needs led to higher probability of uncontrolled SBP. To mitigate model bias and elucidate differences in predictive variables, two separate models were trained for Black and White patients. Black patients face a 4.7

conclusionsModels using non-clinical factors can predict which patients exhibit poorly controlled hypertension. Racial and SDoH variables are significant predictors but lead to biased predictive models. Race-specific models are not sufficient to resolve such biases and require further decision threshold tuning. A host of structural socioeconomic factors are identified to be targeted to reduce disparities in hypertension control.

Indexed as

HypertensionRacismSocial Determinants of HealthAdultAgedBlack or African AmericanBostonFemaleHumansMaleMiddle AgedRetrospective StudiesWhiteHypertensionMachine learningRacial biasSocial determinants of health

Identifiers

PMID39901187
PMCPMC11792567

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.