Evidence mapPaperPMID 39901552Full record

ReviewCurrent medicinal chemistry2025

Lipid Biochemistry and its Role in Human Diseases.

Amine Nehaoua, Amin Gasmi, Asma Gasmi Benahmed, Sadaf Noor, Geir Bjørklund

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Total alkaloids fromFrontiers in pharmacology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Amine NehaouaLaboratory of Physical Activity Sciences and Public Health, Mohamed Lamine Debaghine Setif 2 University, Setif, Algeria.
Amin GasmiSociété Francophone de Nutrithérapie et de Nutrigénétique Appliquée, Villeurbanne, France.
Asma Gasmi BenahmedAcadémie Internationale de Médecine Dentaire Intégrative, Paris, France.
Sadaf NoorInstitute of Molecular Biology and Biotechnology, Bahauddin Zakariya University, Multan, Pakistan.
Geir BjørklundCouncil for Nutritional and Environmental Medicine, Mo i Rana, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lipids play a variety of roles in living systems. They are a source of extremely high energy and a part of almost all signaling and biological processes. Despite the liver being the hub of lipid metabolism, lipid metabolism occurs across the human body. Any perturbation in the lipid metabolism or lipid storage systems can lead to diseases or disorders that can hamper the normal functioning of the human body. Lipids have been explored for their role in cancers. The intake of saturated fatty acids has been found to increase the metastasis and growth of cancerous cells. The role of lipids has also been studied in brain diseases. In Tay-Sachs disease, the inability to metabolize GM2 ganglioside alters normal nerve cell functioning. Similarly, lipids also play critical roles in Parkinson's and Alzheimer's disease. Moreover, atherosclerosis is a leading cause of cardiovascular diseases and brain stroke. Dyslipidemia or excess fatty acids is a leading cause of non-alcoholic fatty liver disease, insulin resistance, and diabetes mellitus. Dyslipidemia also leads to jaundice, which, in turn, can seriously damage the kidneys. This review focuses on the various human diseases occurring because of lipid metabolism.

Indexed as

Lipid MetabolismLipidsAlzheimer DiseaseCardiovascular DiseasesDiabetes MellitusDyslipidemiasHumansNeoplasmsParkinson DiseaseLipidsatherosclerosiscancersdyslipidemia.human diseaseslipid metabolismLipids

Identifiers

PMID39901552

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.