ArticleBulletin of pharmaceutical sciences2024
MACROLACTONES AND MACROLIDES FROM PLANT ENDOPHYTIC FUNGI, CHEMICAL SCAFFOLDS, BIOLOGICAL ACTIVITIES AND SPECTROSCOPY: A COMPREHENSIVE REVIEW.
Article in Bulletin of pharmaceutical sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Background: The pandemic of COVID-19 has stressed the exaggerated demand for innovative treatments, prompting the search for new sources. Plant endophytic fungi produce a diverse array of biologically active compounds, including macrolides and macrolactones with varying activities. Aim of the Study: In this review we give an updated overview of natural macrolides and macrololactones from plant endophytes addressing original studies published up to June 2023. Results: Over the preceding ten years, 91 macrolides with 80 novel compounds with cytotoxic, antibacterial, antifungal, and α-glucosidase inhibitory activities. Unfortunately, the number of novel chemicals identified from marine or bacterial endophytes in the same period is substantially lower. Accordingly, further study on plant endophytes, which are critical for drug research and the development of novel medicines, including antitumors, antivirals, antibacterials, and antimalarials, should be conducted. A report of the
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Registered trials
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