Evidence map›Paper›PMID 39903304›Full record

ArticleFish physiology and biochemistry2025

Dietary L-carnitine supplementation recovers the hepatic damage induced by high-fat diet in Nile tilapia (Oreochromis niloticus L.) via activation of Nrf2/Keap pathway and inhibition of pro-inflammatory cytokine.

Doaa H Assar, Abdallah S Salah, Aya G Rashwan, Ibrahim I Al-Hawary, Basma M Hendam, Ahmed Elsheshtawy, Amer Al Ali, Humood Al Shmrany, Zizy I Elbialy

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In one paragraph

Article in Fish physiology and biochemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Doaa H AssarClinical Pathology Department, Faculty of Veterinary Medicine, Kafrelsheikh University, Kafrelsheikh, 33516, Egypt.ORCID http://orcid.org/0000-0001-7718-3560
Abdallah S SalahDepartment of Aquaculture, Faculty of Aquatic and Fisheries Sciences, Kafrelsheikh University, Kafrelsheikh, 33516, Egypt.
Aya G RashwanDepartment of Fish Processing and Biotechnology, Faculty of Aquatic and Fisheries Sciences, Kafrelsheikh University, Kafrelsheikh, 33516, Egypt.
Ibrahim I Al-HawaryDepartment of Fish Processing and Biotechnology, Faculty of Aquatic and Fisheries Sciences, Kafrelsheikh University, Kafrelsheikh, 33516, Egypt.
Basma M HendamDepartment of Husbandry and Development of Animal Wealth, Faculty of Veterinary Medicine, Mansoura University, Mansoura, 35516, Egypt.
Ahmed ElsheshtawyInstitute of Aquaculture, Faculty of Natural Sciences, University of Stirling, Stirling, FK9 4LA, UK.ORCID http://orcid.org/0000-0003-3811-4997
Amer Al AliDepartment of Medical Laboratory Sciences, College of Applied Medical Sciences, University of Bisha, 255, Al Nakhil, 67714, Bisha, Saudi Arabia.
Humood Al ShmranyDepartment of Medical Laboratory , College of Applied Medical Sciences, Prince Sattam Bin Abdulaziz University, 11942, Alkharj, Saudi Arabia.ORCID http://orcid.org/0009-0000-3024-8494
Zizy I ElbialyDepartment of Fish Processing and Biotechnology, Faculty of Aquatic and Fisheries Sciences, Kafrelsheikh University, Kafrelsheikh, 33516, Egypt. zeze_elsayed@fsh.kfs.edu.eg.ORCID http://orcid.org/0000-0002-1654-0015

Funding

Prince Sattam bin Abdulaziz University PSAU/2024/R/ 1445
6 · The paper itself

Abstract

A feeding trial for 8 weeks was performed to explore whether nutritional supplementation of L-carnitine may minimize the adverse effects of high-fat diet (HFD) on tilapia growth performance, antioxidant, immune parameters, inflammatory response, histopathology of liver, kidney, and intestine, as well as hepatic lipid metabolism aiming to reveal the mechanism and providing a shred of molecular evidence in Nile tilapia (Oreochromis niloticous). Six groups of the Nile tilapia (17.13

Indexed as

CarnitineCichlidsDiet, High-FatFish DiseasesAnimal FeedAnimalsCytokinesDietary SupplementsFish ProteinsLipid MetabolismLiverNF-E2-Related Factor 2Signal TransductionCarnitineCytokinesFish ProteinsNF-E2-Related Factor 2Growth performanceHigh-fat dietImmune responseInflammationl-CarnitineLipid metabolism

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.