Evidence map›Paper›PMID 39904778›Full record

ReviewDermatologie (Heidelberg, Germany)2025

[Vitiligo-update on pathogenesis, diagnostics and therapy].

Paloma Seidel, Markus Böhm

Abstract readReviewEnglish Abstract
PubMed Publisher
In one paragraph

Review in Dermatologie (Heidelberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Paloma SeidelKlinik für Hautkrankheiten, Universitätsklinikum Münster, Von-Esmarch-Str. 58, 48149, Münster, Deutschland.
Markus BöhmKlinik für Hautkrankheiten, Universitätsklinikum Münster, Von-Esmarch-Str. 58, 48149, Münster, Deutschland. bohmm@uni-muenster.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vitiligo is a common skin disease leading to depigmentation that is associated with progressive destruction of melanocytes. The main subtype, nonsegmental vitiligo (NSV), is considered a chronic autoimmune disease leading to activation of melanocyte-specific CD8+ lymphocytes and development of a cutaneous immune memory. Vitiligo can result in significant impairment of quality of life and is associated with a number of comorbidities. Despite the existence of national guidelines and international treatment recommendations, there is a strong need for improved health care for patients with vitiligo. The options in the treatment algorithm for vitiligo are similar and consisted until recently of only topical and systemic corticosteroids, topical calcineurin inhibitors, phototherapy, and surgical interventions. New insights into the pathobiological role of the interferon signature in vitiligo have most recently contributed to the approval of the first vitiligo-specific therapy with the topical Janus kinase 1/2 inhibitor ruxolitinib for patients with NSV.

Indexed as

VitiligoAdrenal Cortex HormonesCalcineurin InhibitorsHumansMelanocytesNitrilesPhototherapyPyrazolesPyrimidinesAdrenal Cortex HormonesCalcineurin InhibitorsNitrilesPyrazolesPyrimidinesruxolitinibCalcineurin inhibitorsComorbidityJanus kinase inhibitorPhototherapyTopical corticosteroids

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.