Evidence map›Paper›PMID 39907096›Full record

ArticleThe Journal of physiology2025

Multiple carbamylation events are required for differential modulation of Cx26 hemichannels and gap junctions by CO

Sarbjit Nijjar, Deborah Brotherton, Jack Butler, Valentin-Mihai Dospinescu, Harry G Gannon, Victoria Linthwaite, Martin Cann, Alexander Cameron, Nicholas Dale

Abstract read
In one paragraph

Article in The Journal of physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. COeLife · 2026
    Article
  3. Connexin50 hemichannels are opened by COFrontiers in physiology · 2026
    Article
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sarbjit NijjarSchool of Life Sciences, University of Warwick, Coventry, UK.
Deborah BrothertonSchool of Life Sciences, University of Warwick, Coventry, UK.
Jack ButlerSchool of Life Sciences, University of Warwick, Coventry, UK.
Valentin-Mihai DospinescuSchool of Life Sciences, University of Warwick, Coventry, UK.
Harry G GannonDepartment of Biosciences, Durham University, Durham, UK.
Victoria LinthwaiteDepartment of Biosciences, Durham University, Durham, UK.
Martin CannDepartment of Biosciences, Durham University, Durham, UK.
Alexander CameronSchool of Life Sciences, University of Warwick, Coventry, UK.
Nicholas DaleSchool of Life Sciences, University of Warwick, Coventry, UK.

Funding

Leverhulme Trust RPG-2015-090 F/00/128/AUUKRI | Biotechnology and Biological Sciences Research Council (BBSRC) BB/S015132/1UKRI | Biotechnology and Biological Sciences Research Council (BBSRC) BB/T00746X/1UKRI | Biotechnology and Biological Sciences Research Council (BBSRC) BB/T013346/1UKRI | Medical Research Council (MRC) MR/N014294/1UKRI | Medical Research Council (MRC) MR/P010393/1
6 · The paper itself

Abstract

CO

Indexed as

Carbon DioxideConnexin 26Gap JunctionsAnimalsChickensConnexinsHEK293 CellsHumansLysineProtein CarbamylationCarbon DioxideConnexin 26ConnexinsGJB2 protein, humanLysinecarbamylationcarboxylationconnexincryo‐EMgap junction channelhemichannel

Identifiers

PMID39907096
PMCPMC11870076

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.