Evidence mapPaperPMID 39907170Full record

ArticleDrug development research2025

Discovery of Hydrazine Clubbed Thiazoles as Potential Antidiabetic Agents: Synthesis, Biological Evaluation, and Molecular Docking Studies.

Betül Kaya, Hakan Tahtacı, Bilge Çiftçi, Hatice Esra Duran, Adem Necip, Mesut Işık, Şükrü Beydemir

Abstract read
In one paragraph

Article in Drug development research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Design, Synthesis,Molecules (Basel, Switzerland) · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Betül KayaDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Zonguldak Bulent Ecevit University, Zonguldak, Turkey.ORCID 0000-0002-1713-9485
Hakan TahtacıDepartment of Chemistry, Faculty of Science, Karabuk University, Karabuk, Turkey.
Bilge ÇiftçiVocational School of Health Services, Bilecik Şeyh Edebali University, Bilecik, Turkey.ORCID 0000-0002-4153-1209
Hatice Esra DuranDepartment of Medical Biochemistry, Faculty of Medicine, Kafkas University, Kars, Turkey.
Adem NecipDepartment of Pharmacy Services, Vocational School of Health Services, Harran University, Şanlıurfa, Turkey.
Mesut IşıkDepartment of Bioengineering, Faculty of Engineering, Bilecik Şeyh Edebali University, Bilecik, Turkey.
Şükrü BeydemirDepartment of Biochemistry, Faculty of Pharmacy, Anadolu University, Eskişehir, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, hydrazine clubbed thiazole derivatives (3a-3j) were obtained by Hantzsch thiazole synthesis and characterized by MS,

Indexed as

Enzyme InhibitorsHydrazinesHypoglycemic AgentsThiazolesAldehyde Reductasealpha-AmylasesDrug DiscoveryGlycoside Hydrolase InhibitorsHumansMolecular Docking SimulationStructure-Activity RelationshipAldehyde Reductasealpha-AmylasesEnzyme InhibitorsGlycoside Hydrolase InhibitorshydrazineHydrazinesHypoglycemic AgentsThiazolesADMEaldose reductasealpha‐amylasealpha‐glucosidaseantidiabeticmolecular dockingthiazole

Identifiers

PMID39907170
PMCPMC11795734

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.