Evidence map›Paper›PMID 39907304›Full record

SynthesisNutrition reviews2025

ILSI Europe Systematic Review: The Impact of Digestible and Nondigestible Carbohydrate Consumption for Toddlers (1-4 Years) in Relation to Health Outcomes.

Bartlomiej M Zalewski, Gisela A Weiss, Cristina Campoy, Tamás Decsi, Elisabetta Di Profio, Renaud Mestdagh, Maryam Rakhshandehroo, Hania Szajewska, Stephan Theis, Elaine E Vaughan and 2 more

Abstract readSystematic Review
In one paragraph

Synthesis in Nutrition reviews, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Bartlomiej M ZalewskiDepartment of Pediatrics, The Medical University of Warsaw, 02-091 Warsaw, Poland.ORCID 0000-0002-5383-9905
Gisela A WeissYili Innovation Center Europe, 6708 WH Wageningen, The Netherlands.ORCID 0000-0002-5983-5569
Cristina CampoyDepartment of Pediatrics, School of Medicine.ORCID 0000-0002-9860-6785
Tamás DecsiDepartment of Pediatrics, Faculty of Medicine, University of Pécs, Pécs, Hungary.
Elisabetta Di ProfioDepartment of Health Science, University of Milan, Milan, Italy.ORCID 0000-0002-6155-0546
Renaud MestdaghCargill R&D Centre Europe BV, B-1800 Vilvoorde, Belgium.
Maryam RakhshandehrooDanone Research and Innovation, 3584 CT Utrecht, The Netherlands.ORCID 0009-0006-4905-2401
Hania SzajewskaDepartment of Pediatrics, The Medical University of Warsaw, 02-091 Warsaw, Poland.ORCID 0000-0002-4596-2874
Stephan TheisBENEO/Suedzucker Group, 67283 Obrigheim, Germany.ORCID 0000-0002-5627-855X
Elaine E VaughanSensus (Royal Cosun), 4704 RA Roosendaal, The Netherlands.ORCID 0009-0007-5712-3617
Elvira VerduciMetabolic Disease Unit, Department of Pediatrics, Vittore Buzzi Hospital, University of Milan, Milan, Italy.ORCID 0000-0003-2111-3111
Ching-Yu ChangInternational Life Sciences Institute, European Branch, 1200 Brussels, Belgium.ORCID 0009-0003-4867-8654

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextEarly dietary habits play a crucial role in shaping long-term health outcomes. Understanding the effects of different carbohydrate types on physiological markers is essential for developing evidence-based nutritional guidelines for toddlers.

objectiveThe aim was to systematically evaluate the impact of both digestible and nondigestible carbohydrate intake during early childhood (1-4 years of age) on various health outcomes, including growth patterns, metabolic parameters, and the development of risk of cardiovascular diseases. DATA SOURCES: PubMed, Embase, and CENTRAL databases were searched up to April 2022 to identify studies investigating carbohydrate consumption in toddlers. DATA EXTRACTION: The types of carbohydrates consumed, their sources, and their associations with growth parameters and metabolic markers were extracted. Thirty-one publications, including 18 cohort studies and 2 randomized controlled trials, were included. DATA ANALYSIS: The risk of bias was assessed using the Mixed Methods Appraisal Tool. A narrative synthesis was performed, with a visual summary table of the direction of effects.

conclusionIn toddlers, the negative impact on health risks later in life is more pronounced for digestible dietary carbohydrate intake in liquid forms, such as sugar-sweetened beverages and fruit juice, compared with solid forms. Higher nondigestible carbohydrate (dietary fiber) intake during early childhood showed a beneficial trend on later lipid profile. Further studies are required to comprehensively assess the effect of digestible and nondigestible carbohydrate intake in toddlers on cognitive and psychomotor development, infections, bowel function, and gut microbiota.

Indexed as

DietDietary CarbohydratesDigestionCardiovascular DiseasesChild DevelopmentChild, PreschoolDietary FiberEuropeHumansInfantDietary CarbohydratesDietary Fiberbeveragebody compositionbowel habitcarbohydrateglycemicsugar

Identifiers

PMID39907304
PMCPMC12066953

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.