Evidence map›Paper›PMID 39907951›Full record

ReviewInflammopharmacology2025

Herbal remedies for oral and dental health: a comprehensive review of their multifaceted mechanisms including antimicrobial, anti-inflammatory, and antioxidant pathways.

Mohamed A Anwar, Ghadir A Sayed, Dina M Hal, Mohamed S Abd El Hafeez, Abdel-Aziz S Shatat, Aya Salman, Nehal M Eisa, Asmaa Ramadan, Riham A El-Shiekh, Shymaa Hatem and 1 more

Abstract readReview
In one paragraph

Review in Inflammopharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Nano-Enabled Advances in Tea Tree Essential Oil (Materials (Basel, Switzerland) · 2026
    Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Review
  12. Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Chemical Profiling ofPlants (Basel, Switzerland) · 2025
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mohamed A AnwarDepartment of Pharmacognosy, Faculty of Pharmacy, Cairo University, Cairo, 11562, Egypt.
Ghadir A SayedDepartment of Biochemistry, Faculty of Pharmacy, Egyptian Russian University, Badr, Cairo, 11829, Egypt.
Dina M HalDepartment of Pharmacognosy, Faculty of Pharmacy, Suez Canal University, Ismailia, 41522, Egypt.
Mohamed S Abd El HafeezDepartment of Pharmacy, Kut University College, Al Kut, Wasit, 52001, Iraq.
Abdel-Aziz S ShatatDepartment of Pharmacology and Toxicology, Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt.
Aya SalmanDepartment of Biochemistry, Faculty of Pharmacy, Egyptian Russian University, Badr, Cairo, 11829, Egypt.
Nehal M EisaClinical Research Department at Giza Health Affairs Directorate, MOHP, Giza, Egypt.
Asmaa RamadanDepartment of Biochemistry, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa, Egypt.
Riham A El-ShiekhDepartment of Pharmacognosy, Faculty of Pharmacy, Cairo University, Cairo, 11562, Egypt. riham.adel@pharma.cu.edu.eg.ORCID http://orcid.org/0000-0002-3179-3352
Shymaa HatemDepartment of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Future University in Egypt, Cairo, Egypt. shaimaa.hatem@fue.edu.eg.
Shaza H AlyDepartment of Pharmacognosy, Faculty of Pharmacy, Badr University in Cairo (BUC), Cairo, 11829, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Across diverse cultures, herbal remedies have been used to alleviate oral discomfort and maintain dental hygiene. This review presents studies on herbal remedies with remarkable antimicrobial, anti-inflammatory, antioxidant, anticancer, anticaries, analgesic, and healing properties. The manuscripts demonstrate the depth of scientific inquiry into herbal remedies used for the management of various oral and dental health conditions. These include gingivitis, oral ulcers, mucositis, periodontitis, oral pathogens, carcinoma, xerostomia, and dental caries. Researchers have investigated the phytochemical and pharmacological properties of plant-derived compounds and their extracts evaluated their interactions with oral pathogens and inflammatory processes. The convergence of traditional knowledge and rigorous scientific investigation offers a compelling narrative, fostering a deeper understanding of herbal remedies as viable alternatives to conventional dental interventions. This work has the potential to provide patients with access to gentle, yet effective solutions, and simultaneously offer dental health professionals the opportunity to enrich their knowledge, and ability to provide personalized, holistic care. This review highlights the symbiotic relationship between herbal medicine and scientific understanding, emphasizing the importance of disseminating this knowledge to benefit both practitioners and patients, enabling evidence-based decision-making in dental care. The exploration of herbal remedies offers a promising alternative, potentially mitigating some of these side effects while promoting oral health in a more natural and holistic manner.

Indexed as

Anti-Infective AgentsAnti-Inflammatory AgentsAntioxidantsMouth DiseasesOral HealthPlant PreparationsAnimalsHumansPhytotherapyPlant ExtractsPlants, MedicinalAnti-Infective AgentsAnti-Inflammatory AgentsAntioxidantsPlant ExtractsPlant PreparationsAnti-inflammatoryComplementary medicineDental careHerbal remediesNanotechnologyOral health

Identifiers

PMID39907951
PMCPMC11914039

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.