SynthesisObesity surgery2025
The Efficacy of Glucagon-like Peptide-1 (GLP-1) Receptor Agonists for Insufficient Weight Loss or Regain After Metabolic/Bariatric Surgery: A Systematic Review and Meta-analysis.
Synthesis in Obesity surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Glucagon-Like Peptide-1 Receptor Agonists vs. Bariatric Endoscopy: A Systematic Review and Meta Analysis of Efficacy, Safety, and Metabolic Outcomes.Obesity surgery · 2026Pooled it
- The role of glucagon-like peptide-1 receptor agonists in weight regain treatment or prevention after bariatric surgery: a systematic review and meta-analysis.Eating and weight disorders : EWD · 2025Pooled it
- Early Adjuvant Treatment with Semaglutide After Sleeve Gastrectomy in Patients with Class II-III Obesity: A Prospective Non-Randomized Controlled Study.Obesity surgery · 2026Article
- Metabolic Outcomes and Recurrent Weight Gain 10 Years After Roux-en-Y Gastric Bypass, a Longitudinal Cohort Study.Obesity surgery · 2026Article
- Echocardiographic evaluation and clinical implications of cardiac remodeling in obesity.Journal of echocardiography · 2026Review
- Long-term outcomes of metabolic and bariatric surgery: a 10-year study of effectiveness and predictors.International journal of obesity (2005) · 2026Article
- Beyond the Procedure: Revisiting the Technical Determinants of Sleeve Gastrectomy and Roux-en-Y Gastric Bypass.Journal of metabolic and bariatric surgery · 2026Review
- Long-Term Outcomes of Pouch Resizing with Ring Augmentation for Dumping Syndrome and Weight Trajectory after Roux-en-Y Gastric Bypass: A Single-Center Experience.Obesity surgery · 2026Article
- The effect of endoscopic transoral outlet reduction (TORe) on weight recidivism and insufficient weight loss following one-anastomosis gastric bypass (OAGB). : Tore after OAGB for weight recidivism.Langenbeck's archives of surgery · 2026Article
- Nutritional Vulnerability in RYGB Unmasked by GLP-1 Therapy.ACG case reports journal · 2026Article
- Optimizing Safety and Outcomes in Metabolic/Bariatric Surgery: A Conceptual Framework for Staged Minimally Invasive Treatment.Obesity surgery · 2026Review
- Primary Care Providers Perspectives of GLP-1 Receptor Agonists to Manage Recurrent Weight Gain after Metabolic Bariatric Surgery - a Qualitative Study.Obesity surgery · 2026Article
- Analysis of factors influencing weight regain after bariatric-metabolic surgery in obesity hypoventilation syndrome patients based on gastrointestinal peptide hormones.Journal of medical biochemistry · 2025Article
- GLP-1 Agonists in Aesthetic Surgery: Implications for Perioperative Outcomes and Body Contouring Procedures.Aesthetic plastic surgery · 2025Article
- The Role of Physical Activity in Minimizing Recurrence of Weight Gain Following Metabolic and Bariatric Surgery: Current Evidence and Suggestions for Advancing Future Research.Current obesity reports · 2025Review
- Weight Cycling Deregulates Eating Behavior in Mice via the Induction of Durable Gut Dysbiosis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Eating Disorders in the Context of Metabolic and Bariatric Surgery: Current Status and Future Directions.Current obesity reports · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Metabolic and bariatric surgery (MBS) is a successful surgical option for obesity. However, many patients can experience insufficient weight loss and weight regain post-operatively. Glucagon-like peptide-1 (GLP-1) receptor agonists have become available for effective weight loss treatment due to their effects of suppressing appetite, slowing gastric emptying, and promoting fat loss. This systematic review aims to evaluate the efficacy of using GLP-1 agonists to treat insufficient weight loss or regain after metabolic/bariatric surgery. Pooled analysis demonstrated that GLP-1 agonists have a moderate effect on weight loss after failed weight loss or weight regain following MBS, with a Cohen's d-score of 0.470 (p ≤ 0.001). GLP-1 agonists show promise and deserve additional research as part of the standard of care following MBS with insufficient weight loss.
Indexed as
Identifiers
39910018What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.