Evidence map›Paper›PMID 39910240›Full record

ReviewNature reviews. Immunology2025

B cells in non-lymphoid tissues.

Abrar Samiea, George Celis, Rashi Yadav, Lauren B Rodda, Joshua M Moreau

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. B cells in cancer: functions, mechanisms and therapeutic advances.Signal transduction and targeted therapy · 2026
    Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Hidden immune memory niches in inflammatory skin diseases.bioRxiv : the preprint server for biology · 2026
    Article
  9. Review
  10. Review
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Abrar Samiea *Department of Cell, Developmental and Cancer Biology, Oregon Health & Science University, Portland, OR, USA.
George Celis *Department of Molecular Microbiology and Immunology, Oregon Health & Science University, Portland, OR, USA.
Rashi YadavCancer Early Detection Advanced Research Center, Oregon Health & Science University, Portland, OR, USA.
Lauren B RoddaDepartment of Molecular Microbiology and Immunology, Oregon Health & Science University, Portland, OR, USA. rodda@ohsu.edu.ORCID http://orcid.org/0000-0001-7763-8166
Joshua M MoreauDepartment of Cell, Developmental and Cancer Biology, Oregon Health & Science University, Portland, OR, USA. moreauj@ohsu.edu.ORCID http://orcid.org/0000-0002-1227-1508

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

B cells have long been understood to be drivers of both humoral and cellular immunity. Recent advances underscore this importance but also indicate that in infection, inflammatory disease and cancer, B cells function directly at sites of inflammation and form tissue-resident memory populations. The spatial organization and cellular niches of tissue B cells have profound effects on their function and on disease outcome, as well as on patient response to therapy. Here we review the role of B cells in peripheral tissues in homeostasis and disease, and discuss the newly identified cellular and molecular signals that are involved in regulating their activity. We integrate emerging data from multi-omic human studies with experimental models to propose a framework for B cell function in tissue inflammation and homeostasis.

Indexed as

B-LymphocytesAnimalsHomeostasisHumansInflammationNeoplasms

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.