ArticleScientific reports2025
Ionized and total magnesium levels and health outcomes in patients with type 2 diabetes mellitus.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- The effect of oral magnesium supplementation on glycemic control and metabolic parameters in type 2 diabetes mellitus: a double-blind randomized controlled trial.Frontiers in endocrinology · 2026Trial
- Article
- Dysmagnesemia in the ICU: A Comparative Analysis of Ionized and Total Magnesium Levels and Their Clinical Associations.Metabolites · 2025Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Magnesium (Mg) is a vital trace element in cellular processes, including glucose metabolism and insulin action. This study aimed to assess the prevalence of dysmagnesemia among patients with type 2 diabetes mellitus (T2DM) and its relationship with glycaemic control and diabetic complications. A cross-sectional study was conducted at Sultan Qaboos University Hospital (SQUH) from August 1, 2023, to April 30, 2024. The study included adult patients with T2DM treated with oral hypoglycemic agents (OHA), insulin, glucagon-like-peptide 1 (GLP-1) injections or their combinations. Both ionized (iMg) and total (tMg) concentrations were measured and the iMg/tMg ratio was calculated. A total of 329 patients with T2DM of which179 females (54.4%), were studied. Hypomagnesemia was observed in 10.0% based on iMg concentrations and 56.2% based on tMg concentrations, while hypermagnesemia was observed in 11.85% (iMg) and 1.82% (tMg). A positive correlation was found between iMg and tMg (r = 0.589, p < 0.01). Hypermagnesemia was associated with higher serum creatinine concentrations (p < 0.01) and lower estimated glomerular filtration rate (eGFR) (p = 0.026). An iMg/tMg ratio above 80% was associated with elevated HbA1c levels, while ratios below 60% were associated with diabetic retinopathy and hypertension. Dysmagnesemia was common among patients with T2DM. The iMg/tMg ratio was associated with diabetic control and presence of complications. The iMg/tMg ratio could be further studied as a potential marker for glycemic control.
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