ArticleMetabolic brain disease2025
Sodium butyrate ameliorates mitochondrial oxidative stress and alterations in membrane-bound enzyme activities in pentylenetetrazole-induced kindling rat model.
Article in Metabolic brain disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Urinary organic acid levels and their associations with clinical characteristics in patients with schizophrenia.Metabolomics : Official journal of the Metabolomic Society · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Epilepsy is a chronic neurological disorder manifested through repeatedly recurrent unprovoked seizures. It is a debilitating neurological illness arising from exacerbated hypersynchronous neuronal firing in the brain. Among various factors, oxidative stress has been implicated in the initiation of epileptogenesis and the progression of epileptic seizures. This study investigates the neuroprotective effect of sodium butyrate in a pentylenetetrazole (PTZ)-induced kindling rat model. Male and female Wistar rats were randomly assigned into four groups for each sex. The PTZ groups were administered 40 mg/kg b.w.t intraperitoneally on alternate days for 30 days and a final single dose on the 40th day, while the sodium butyrate groups were administered along with the rat's drinking water (4 g/L). The seizure score, oxidative stress parameter, acetylcholinesterase (AChE), Na
Indexed as
Identifiers
39913006What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.