Evidence mapPaperPMID 39913071Full record

ReviewCurrent oncology reports2025

Weight Management for Fertility-Preservation Therapy in Endometrial Cancer: Opportunities and Challenges.

XiaoDan Li, YiQian Chen, XiaoWei Li, Xiao Yang, Ling Zhou, Yuan Cheng, HongYi Hou, Dandan Yang, Yuanyuan Gong, Haihua Xiao and 1 more

Abstract readReview
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In one paragraph

Review in Current oncology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

XiaoDan LiDepartment of Obstetrics and Gynecology, Peking University People's Hospital, Beijing, 100044, China.
YiQian ChenBeijing Health Vocational College, Beijing, 101101, China.
XiaoWei LiDepartment of Obstetrics and Gynecology, Peking University People's Hospital, Beijing, 100044, China.
Xiao YangDepartment of Obstetrics and Gynecology, Peking University People's Hospital, Beijing, 100044, China.
Ling ZhouDepartment of Obstetrics and Gynecology, Peking University People's Hospital, Beijing, 100044, China.
Yuan ChengDepartment of Obstetrics and Gynecology, Peking University People's Hospital, Beijing, 100044, China.
HongYi HouDepartment of Obstetrics and Gynecology, Peking University People's Hospital, Beijing, 100044, China.
Dandan YangDepartment of Obstetrics and Gynecology, Peking University People's Hospital, Beijing, 100044, China.
Yuanyuan GongDepartment of Obstetrics and Gynecology, Peking University People's Hospital, Beijing, 100044, China.
Haihua XiaoInstitute of Chemistry, Chinese Academy of Sciences, Beijing, 100190, China.
Jianliu WangDepartment of Obstetrics and Gynecology, Peking University People's Hospital, Beijing, 100044, China. wjl12031218@126.com.

Funding

the National Key Technology Research and Developmental Program of China Program Nos. 2022YFC2704400 and 2022YFC2704405
6 · The paper itself

Abstract

purpose of reviewObesity is increasingly recognized as a significant factor impacting the outcomes of fertility-preserving therapies for endometrial cancer (EC). This review explores the effects of glycolipid metabolism on EC and its relationship with body weight. We will examine how excess body weight influences the effectiveness of fertility-preserving treatments and discuss potential mechanisms for effective weight management. Additionally, the review highlights the importance of comprehensive weight management as an adjunct strategy to enhance the efficacy of fertility-preserving interventions, providing insights into how to integrate metabolic health into clinical treatment protocols. RECENT

findingsWeight management can modify the tumor microenvironment by depriving the tumor of nutrients, whereas exercise can enhance immunity, potentially leading to tumor cell death. In addition, progesterone therapy may impede the proliferation of EC cells. Comprehensive weight management can serve as an essential adjuvant treatment for patients undergoing fertility-preserving therapies for EC. In this review, we highlight that comprehensive weight management can serve as a crucial adjuvant treatment for patients undergoing fertility-preserving therapies for endometrial cancer. Targeting glycolipid metabolism and addressing adiposity can improve hormonal balance, reduce inflammation, and enhance fertility outcomes. Further research is necessary to establish specific protocols and evaluate the effectiveness of these strategies in clinical practice.

Indexed as

Endometrial NeoplasmsFertility PreservationObesityFemaleHumansEndometrial cancerFertility-preservationObesityWeight management

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.