Evidence map›Paper›PMID 39913860›Full record

ArticleDiagnosis (Berlin, Germany)2025

Technical aspects and clinical applications of synthetic MRI: a scoping review.

Tancia Pires, Saikiran Pendem, Jaseemudheen M M, Priyanka

Abstract readScoping Review
PubMed Publisher
In one paragraph

Article in Diagnosis (Berlin, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tancia PiresDepartment of Medical Imaging Technology, 76799 Manipal College of Health Professions, Manipal Academy of Higher Education , Manipal, 576104, Karnataka, India.ORCID https://orcid.org/0009-0002-8838-8953
Saikiran PendemDepartment of Medical Imaging Technology, 76799 Manipal College of Health Professions, Manipal Academy of Higher Education , Manipal, 576104, Karnataka, India.
Jaseemudheen M MDepartment of Medical Imaging Technology, K.S. Hegde Medical Academy (KSHEMA), NITTE (Deemed to be University), Mangalore, Karnataka, India.ORCID https://orcid.org/0000-0003-4399-7309
PriyankaDepartment of Medical Imaging Technology, 76799 Manipal College of Health Professions, Manipal Academy of Higher Education , Manipal, 576104, Karnataka, India.ORCID https://orcid.org/0000-0002-9792-6242

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSynthetic magnetic resonance imaging (SyMRI) is a non-invasive, robust MRI technique that generates multiple contrast-weighted images by acquiring a single MRI sequence within a few minutes, along with quantitative maps, automatic brain segmentation, and volumetry. Since its inception, it has undergone technical advancements and has also been tested for feasibility in various organs and pathological conditions. This scoping review comprehensively pinpoints the critical technical aspects and maps the wide range of clinical applications/benefits of SyMRI. CONTENT: A comprehensive search was conducted across five databases, PubMed, Scopus, Web of Science, Embase, and CINAHL Ultimate, using appropriate keywords related to SyMRI. A total of 99 studies were included after a 2-step screening process. Data related to the technical factors and clinical application was charted. SUMMARY: SyMRI provides quantitative maps and segmentation techniques comparable to conventional MRI and has demonstrated feasibility and applications across neuroimaging, musculoskeletal, abdominal and breast pathologies spanning the entire human lifespan, from prenatal development to advanced age. Certain drawbacks related to image quality have been encountered that can be overcome with technical advances, especially AI-based algorithms. OUTLOOK: SyMRI has immense potential for being incorporated into routine imaging for various pathologies due to its added advantage of providing quantitative measurements for more robust diagnostic and prognostic work-up with faster acquisitions and greater post-processing options.

Indexed as

Magnetic Resonance ImagingAlgorithmsBrainHumansImage Processing, Computer-AssistedNeuroimagingautomatic brain segmentationbrain volumetryquantitative MRIsynthetic MRI

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.