Evidence map›Paper›PMID 39915726›Full record

ArticleBiological procedures online2025

Optimizing the Future: A Game Theory to Tumor Therapeutic Strategies.

Fang-Yuan Liu, Xin Liu, Dan-Ni Ding, Shao-Xuan Liu, Jing Xu, Yu-Xin Zhao, Yan-Hong Wang, Feng-Juan Han

Abstract read
In one paragraph

Article in Biological procedures online, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Fang-Yuan LiuHeilongjiang University of Chinese Medicine, Harbin, 150040, China.
Xin LiuHarbin Institute of Technology, Harbin, 150001, China.
Dan-Ni DingHeilongjiang University of Chinese Medicine, Harbin, 150040, China.
Shao-Xuan LiuHeilongjiang University of Chinese Medicine, Harbin, 150040, China.
Jing XuHeilongjiang University of Chinese Medicine, Harbin, 150040, China.
Yu-Xin ZhaoHeilongjiang University of Chinese Medicine, Harbin, 150040, China.
Yan-Hong WangFirst Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, 150040, China. wang.yanhong@163.com.
Feng-Juan HanFirst Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, 150040, China. hanfengjuan2004@163.com.

Funding

Youth Research Project of Heilongjiang Provincial Administration of Chinese Medicine ZHY2024-223
6 · The paper itself

Abstract

backgroundCancer poses significant economic and societal burdens on countries in the coming decades. During chemotherapy, patients frequently encounter adverse reactions. Recent research has revealed that Chinese medicine plays a crucial role in mitigating the side effects of chemotherapy. Therefore, in this article, we propose that the cancer treatment process can be likened to an unequal game. To refine treatment strategies, we suggest employing the Steinberg model to incorporate Chinese medicine into the chemotherapy regimen for tumor treatment.

resultsWe found that when malignant tumors exhibit vigorous proliferation, doctors should administer Chinese medicine in conjunction with chemotherapy drugs, continuously optimizing the therapeutic effect of the Chinese medicine. Upon reaching a specific threshold in the treatment effect of the Chinese medicine, doctors may appropriately augment the dosage of chemotherapy drugs, building upon the initial regimen. Conversely, in cases where the proliferation ability of malignant tumors is weak, the dosage of chemotherapy and the adjuvant therapy with Chinese medicine should be kept in a relatively balanced state. Once the effect of the Chinese medicine attains a particular threshold, the dosage of chemotherapy can be concurrently increased to achieve a superior therapeutic result.

conclusionsFrom a game theory perspective, doctors can devise strategies to minimize drug toxicity and improve tumor treatment outcomes by coordinating the use of chemotherapy drugs with appropriate adjustments to Chinese medicine therapy methods.

Indexed as

Chemotherapy drugsChinese medicineGame theorySteinberg game modelTumor therapeutic strategies

Identifiers

PMID39915726
PMCPMC11800618

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.