Evidence map›Paper›PMID 39915748›Full record

ArticleBMC public health2025

Association of alcohol abstinence with risk of hyperuricemia in rural Chinese adults: the Henan Rural Cohort Study.

Xiaokang Dong, Lulu Zhang, Ning Kang, Huanxiang Zhang, Wei Liao, Xiaotian Liu, Pengling Liu, Lei Yin, Chongjian Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xiaokang DongNHC Key Laboratory of Prevention and Treatment of Cerebrovascular Diseases, Department of Neurology, The First Affiliated Hospital of Zhengzhou University, 1 Zhengzhou University, Zhengzhou, Henan, 450052, PR China.
Lulu ZhangDepartment of Medical Records Management, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, 450001, PR China.
Ning KangDepartment of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing, 100871, China.
Huanxiang ZhangDepartment of Epidemiology and Biostatistics, College of Public Health, Zhengzhou University, 100 Kexue Avenue, Zhengzhou, Henan, 450001, PR China.
Wei LiaoDepartment of Epidemiology and Biostatistics, College of Public Health, Zhengzhou University, 100 Kexue Avenue, Zhengzhou, Henan, 450001, PR China.
Xiaotian LiuDepartment of Epidemiology and Biostatistics, College of Public Health, Zhengzhou University, 100 Kexue Avenue, Zhengzhou, Henan, 450001, PR China.
Pengling LiuDepartment of Nephrology, The Seventh People's Hospital of Zhengzhou, Zhengzhou, Henan, PR China.
Lei YinDepartment of Nephrology, The Seventh People's Hospital of Zhengzhou, Zhengzhou, Henan, PR China. yinlei3008@163.com.
Chongjian WangNHC Key Laboratory of Prevention and Treatment of Cerebrovascular Diseases, Department of Neurology, The First Affiliated Hospital of Zhengzhou University, 1 Zhengzhou University, Zhengzhou, Henan, 450052, PR China. tjwcj2008@zzu.edu.cn.

Funding

Foundation of National Key Program of Research and Development of China 2016YFC0900803Science and Technology Innovation Team Support Plan of Colleges and Universities in Henan Province 21IRTSTHN029
6 · The paper itself

Abstract

backgroundAlcohol drinking can cause hyperuricemia (HUA), but few studies have explored alcohol abstinence's health effects, particularly the abstinence duration on HUA. This study aimed to evaluate the associations of abstinence with HUA in rural Chinese adults.

methodsThis was a cross-sectional study of 38,855 participants (15,371 males and 23,484 females) using the baseline data (2015-2017) from the Henan Rural Cohort Study. A questionnaire survey collected information on alcohol consumption patterns. Multivariate logistic regression analyses were used to evaluate the associations of type of alcoholic beverages, abstinence status and abstinence duration with HUA, respectively. Restricted cubic spline models were applied to visualize the dose-response trend of HUA risk with increasing abstinence duration.

results3,978 cases of 38,855 participants were identified with HUA. Total alcohol intake, including beer, liquor and rice wine intake was significantly associated with the increased risk of HUA, especially for male participants. Compared with current drinkers, former drinkers and non-drinkers presented lower ORs (95%CIs) of 0.686 (0.676, 0.844) and 0.718 (0.649, 0.793) for HUA. Furthermore, the aORs (95%CIs) for those former drinkers with < 5, 6-10 and ≥ 11 years abstinence duration were 0.868 (0.693, 1.086), 0.753 (0.519, 1.092) and 0.717 (0.517, 0.990), respectively. In addition, the risk of HUA decreased with the increasing years of abstinence duration (P for trend < 0.050) and negative linear dose-response associations were observed.

conclusionFormer drinkers were associated with a reduced risk of HUA compared with current drinkers. Moreover, sustained alcohol abstinence could be beneficial for preventing HUA. CLINICAL

trial registrationThe Henan Rural Cohort Study was registered on the Chinese Clinical Trial Register (Registration number: ChiCTR-OOC-15006699). Date of registration: 2015-07-06 http://www.chictr.org.cn/showproj.aspx?proj=11375 .

Indexed as

Alcohol AbstinenceAlcohol DrinkingHyperuricemiaRural PopulationAdultChinaCohort StudiesCross-Sectional StudiesEast Asian PeopleFemaleHumansMaleMiddle AgedRisk FactorsSurveys and QuestionnairesAlcohol abstinenceAlcoholic beveragesDrinking statusHyperuricemiaRural adults

Identifiers

PMID39915748
PMCPMC11800491

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.