Evidence map›Paper›PMID 39920182›Full record

ArticleScientific reports2025

Genomic analysis of Enterobacter cloacae complex from Southern Thailand reveals insights into multidrug resistance genotypes and genetic diversity.

Thunchanok Yaikhan, Kamonnut Singkhamanan, Pawarisa Luenglusontigit, Arnon Chukamnerd, Natakorn Nokchan, Nutwadee Chintakovid, Sarunyou Chusri, Rattanaruji Pomwised, Monwadee Wonglapsuwan, Kittinun Leetanaporn and 2 more

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. First Report ofFoods (Basel, Switzerland) · 2026
    Article
  3. Draft genome sequence ofMicrobiology resource announcements · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Thunchanok YaikhanDepartment of Biomedical Sciences and Biomedical Engineering, Faculty of Medicine, Prince of Songkla University, Songkhla, 90110, Thailand.
Kamonnut SingkhamananDepartment of Biomedical Sciences and Biomedical Engineering, Faculty of Medicine, Prince of Songkla University, Songkhla, 90110, Thailand.
Pawarisa LuenglusontigitDepartment of Biomedical Sciences and Biomedical Engineering, Faculty of Medicine, Prince of Songkla University, Songkhla, 90110, Thailand.
Arnon ChukamnerdDivision of Infectious Diseases, Department of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Songkhla, 90110, Thailand.
Natakorn NokchanDepartment of Biomedical Sciences and Biomedical Engineering, Faculty of Medicine, Prince of Songkla University, Songkhla, 90110, Thailand.
Nutwadee ChintakovidDepartment of Biomedical Sciences and Biomedical Engineering, Faculty of Medicine, Prince of Songkla University, Songkhla, 90110, Thailand.
Sarunyou ChusriDivision of Infectious Diseases, Department of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Songkhla, 90110, Thailand.
Rattanaruji PomwisedDivision of Biological Science, Faculty of Science, Prince of Songkla University, Hatyai, Songkhla, 90110, Thailand.
Monwadee WonglapsuwanDivision of Biological Science, Faculty of Science, Prince of Songkla University, Hatyai, Songkhla, 90110, Thailand.
Kittinun LeetanapornDepartment of Biomedical Sciences and Biomedical Engineering, Faculty of Medicine, Prince of Songkla University, Songkhla, 90110, Thailand.
Surasak SangkhathatTranslational Medicine Research Center, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand.
Komwit SurachatDepartment of Biomedical Sciences and Biomedical Engineering, Faculty of Medicine, Prince of Songkla University, Songkhla, 90110, Thailand. komwit.s@psu.ac.th.

Funding

the National Science, Research and Innovation Fund (NSRF) and Prince of Songkla University MED6701384athe NSRF via the Program Management Unit for Human Resources & Institutional Development, Research and Innovation B13F660074
6 · The paper itself

Abstract

In this study, we conducted a comprehensive investigation into the Enterobacter cloacae complex (ECC), a group of notorious pathogens responsible for various hospital-acquired infections. We aimed to gain critical insights into antimicrobial resistance profiles and genomic diversity among 17 ECC isolates, which were previously collected as part of a short-term surveillance effort for 6 months in 2019. We identified two novel sequence types (ST-1936 in E. bugandensis PSU30 and ST-1937 in E. roggenkampii PSU45) among the 14 distinct STs identified in our ECC isolates. Furthermore, our expanded investigation revealed 296 novel STs within the NCBI Reference Sequence database. We identified six isolates carrying the mcr-9 gene, highlighting a significant concern in antimicrobial resistance (AMR). These genes confer a reduced susceptibility to colistin, a critical last-resort drug for the treatment of multidrug-resistant (MDR) infection. In addition to the AMR complexity, we found that three isolates carried the bla

Indexed as

Drug Resistance, Multiple, BacterialEnterobacter cloacaeEnterobacteriaceae InfectionsGenetic VariationAnti-Bacterial AgentsCross InfectionGenome, BacterialGenomicsGenotypeHumansMicrobial Sensitivity TestsPhylogenyThailandAnti-Bacterial AgentsComprehensive genomic profilingEnterobacter cloacae complexNovel STWhole genome sequencing

Identifiers

PMID39920182
PMCPMC11806111

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.