Evidence map›Paper›PMID 39920754›Full record

ArticleItalian journal of pediatrics2025

Hospitalizations for bronchiolitis among infants before and after the SARS-CoV-2 pandemic: an area-based study of the Emilia-Romagna Region, Italy.

Elisa Ballardini, Marco Manfrini, Silvia Fattori, Elena Pellacani, Branislava Ćosić, Giancarlo Gargano, Alberto Berardi

Registry-linked trialAbstract read
In one paragraph

Article in Italian journal of pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07682844 (Impact of Outpatient Respiratory Physiotherapy on Hospitalizations and Costs in Infants With Acute Viral Bronchiolitis), which is not on this map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07682844 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Impact of Outpatient Respiratory Physiotherapy on Hospitalizations and Costs in Infants With Acute Viral Bronchiolitis: A Quasi-Experimental Study in Public Health Services in Sorocaba.

TypeinterventionalSponsorUniversity of Sao PauloRan2026 to 2027Enrolled1,000ConditionsAcute Viral BronchiolitisArmsOutpatient Respiratory Physiotherapy
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Elisa BallardiniNeonatal Intensive Care Unit, Dept. of Medical Sciences, University Hospital of Ferrara, IMER Registry (Emilia Romagna Registry of Birth Defects), University of Ferrara, Ferrara, Italy. elisa.ballardini@unife.it.ORCID http://orcid.org/0000-0002-8813-1835
Marco ManfriniIMER Registry (Emilia Romagna Registry of Birth Defects), University Hospital of Ferrara, Ferrara, Italy.ORCID http://orcid.org/0000-0003-3154-9269
Silvia FattoriPediatric Postgraduate School, University of Ferrara, Ferrara, Italy.
Elena PellacaniPediatric Postgraduate School, University of Modena and Reggio Emilia, Modena, Italy.
Branislava ĆosićPediatric Postgraduate School, University of Modena and Reggio Emilia, Modena, Italy.ORCID http://orcid.org/0009-0009-2934-5620
Giancarlo GarganoNeonatal Intensive Care Unit, Azienda Unità Sanitaria Locale-IRCCS, Reggio Emilia, Italy.
Alberto BerardiNeonatal Intensive Care Unit, Policlinico University Hospital, Modena, Italy.ORCID http://orcid.org/0000-0002-3534-7499

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBronchiolitis is the most frequent lower respiratory tract infection and a leading cause of hospitalization in infants. Our aim was to assess the incidence and characteristics of bronchiolitis requiring hospital admission in an Italian region before and after the SARS-CoV-2 pandemic.

methodsThis area-based retrospective study analyses 4,396 hospital discharge records (HDR) of children under 1 year of age admitted with a diagnosis of bronchiolitis (ICD9-CM codes 466.11 and 466.19), in Emilia-Romagna (Italy) from January1st, 2018 to December 31th, 2021. Weighted t-testing and Z-testing was carried out.

resultsin the study period, 2-4% of infants were admitted for bronchiolitis (10% of all admissions under 1 year) and 59% of them were aged less than 90 days. After a significant decrease in 2020, bronchiolitis resurged in 2021, and Respiratory Syncytial Virus (RSV) cases reached 82%. RSV cases were more likely to undergo non-invasive ventilation (NIV), oxygen supplementation and to receive i.v. (intravenous) infusions. There was an overall increasing trend in NIV and oxygen supplementation, and a decreasing trend in chest X-rays.

conclusionsThis area-based study shows reduced hospital admissions due to bronchiolitis during the SARS-CoV-2 pandemic and a resurgence of RSV infection after the easing of preventive measures. We also provide information on length of stay and need for hospital treatments. These area-based information will be helpful in assessing the impact of future universal prevention measures.

Indexed as

BronchiolitisCOVID-19HospitalizationFemaleHumansIncidenceInfantInfant, NewbornItalyMalePandemicsRetrospective StudiesSARS-CoV-2BronchiolitisEpidemiologyHospitalizationInfantsRespiratory syncytial virusSARS-CoV-2

Identifiers

PMID39920754
PMCPMC11806670

What Socratic holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.