Evidence map›Paper›PMID 39921708›Full record

ReviewDrug safety2025

Drug Induced Liver Injury: Highlights and Controversies in the 2023 Literature.

Harjit Singh, Bryce F Kunkle, Angela R Troia, Advait M Suvarnakar, Ade C Waterman, Yadana Khin, Serena Y Korkmaz, Corinne E O'Connor, James H Lewis

Abstract readReview
PubMed Publisher
In one paragraph

Review in Drug safety, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Harjit SinghDepartment of Internal Medicine, Medstar Georgetown University Hospital, Washington, DC, USA. harjit.singh@medstar.net.ORCID http://orcid.org/0000-0001-7883-5743
Bryce F KunkleDepartment of Internal Medicine, Medstar Georgetown University Hospital, Washington, DC, USA.
Angela R TroiaDepartment of Internal Medicine, Medstar Georgetown University Hospital, Washington, DC, USA.
Advait M SuvarnakarGeorgetown University School of Medicine, Washington, DC, USA.
Ade C WatermanDepartment of Internal Medicine, Medstar Georgetown University Hospital, Washington, DC, USA.
Yadana KhinDepartment of Internal Medicine, Medstar Georgetown University Hospital, Washington, DC, USA.
Serena Y KorkmazDepartment of Internal Medicine, Medstar Georgetown University Hospital, Washington, DC, USA.
Corinne E O'ConnorDepartment of Internal Medicine, Medstar Georgetown University Hospital, Washington, DC, USA.
James H LewisDivision of Gastroenterology and Hepatology, Medstar Georgetown University Hospital, Washington, DC, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Drug-induced liver injury (DILI) remains an active field of clinical research and investigation with more than 4700 publications appearing in 2023 relating to hepatotoxicity of all causes and injury patterns. As in years past, we have attempted to identify and summarize highlights and controversies from the past year's literature. Several new and novel therapeutic agents were approved by the US Food and Drug Administration (FDA) in 2023, a number of which were associated with significant hepatotoxicity. Updates in the diagnosis and management of DILI using causality scores as well as newer artificial intelligence-based methods were published. Details of newly established hepatotoxins as well as updated information on previously documented hepatotoxic drugs is presented. Significant updates in treatment of DILI were also included as well as reports related to global DILI registries.

Indexed as

Chemical and Drug Induced Liver InjuryDrug-Related Side Effects and Adverse ReactionsArtificial IntelligenceHumansUnited StatesUnited States Food and Drug Administration

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.