ArticleJournal of health, population, and nutrition2025
Correlation between hemoglobin, albumin, lymphocyte, and platelet score and short-term mortality in critically ill patients.
Article in Journal of health, population, and nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Comparative Analysis of Novel Inflammatory and Nutritional Indices (m-HALP, HALP, SII, SIRI) for Risk Stratification in Septic Patients: A Retrospective Cohort Study.Life (Basel, Switzerland) · 2026Article
- Emergency department evaluation of immature granulocytes for complicated acute appendicitis: a retrospective cohort study.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2026Article
- Prognostic value of the HALP score in patients undergoing emergency surgery for gastroduodenal perforation.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2026Article
- Neutrophil-to-Lymphocyte Ratio, Systemic Immune-Inflammation Index, and HALP Score as Predictors of Mortality in Acute Respiratory Distress Syndrome.Journal of clinical medicine · 2026Article
- Association between HALP score and in-hospital outcomes in patients with acute kidney injury: a retrospective cohort study.Scientific reports · 2026Article
- Prognostic value of the early D-dimer/fibrinogen ratio in critically ill patients requiring vascular surgery: a retrospective study.BMC anesthesiology · 2026Article
- Development and validation of a nomogram integrating inflammatory-nutritional-metabolic composite indices for predicting short-term adverse outcomes in hospitalized patients with pneumonia.Frontiers in medicine · 2026Article
- Article
- Relationship Between Nutritional Status and Systemic Immune-Inflammation Indices Across BMI Categories.Nutrients · 2025Article
- Association Between the Hemoglobin, Albumin, Lymphocyte, and Platelet (HALP) Score and Adverse Outcomes in Critically Ill Patients With Acute Myocardial Infarction: A Retrospective Study and Machine Learning Analysis.Reviews in cardiovascular medicine · 2025Article
- The relationship between hemoglobin, albumin, lymphocyte, and platelet (HALP) score and 28-day mortality in patients with sepsis: a retrospective analysis of the MIMIC-IV database.BMC infectious diseases · 2025Article
- Development of a Nomogram for Predicting Multiple Organ Dysfunction in Acute Pancreatitis.Journal of inflammation research · 2025Article
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10 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundHemoglobin, albumin, lymphocyte and platelet (HALP) score is derived from the counts of hemoglobin, albumin, lymphocytes, and platelets. It serves as a valuable tool for assessing both inflammation and nutritional status in critically ill patients. However, there hasn't been a specific study exploring the role of the HALP score in critically ill patients. Additionally, whether the HALP score exhibits an incremental effect on the Sequential Organ Failure Assessment (SOFA) score remains unknown.
methodsIn this study, we used the Medical Information Mart for Intensive Care (MIMIC-IV) version 2.2 database to evaluate the predictive value of HALP score for critically ill patients. The primary outcome investigated was intensive care unit (ICU) death, and the secondary outcomes included in-hospital mortality, ICU length of stay (LOS), hospital LOS, and 28-day mortality.
resultsWe analyzed 20,083 critically ill patients. In logistic regression, a low HALP score (HALP score < 3.56) showed higher risk of ICU death (adjusted odds ratio: 1.41, 95% confidence interval [CI]: 1.25 to 1.59). Additionally, the HALP score improved the predictive ability of the SOFA score (∆Area under curve: 0.009, p < 0.001). In Cox proportional hazards models, a low HALP score (HALP score < 3.2) was also associated with a higher risk of 28-day mortality (adjusted hazard ratio: 1.52, 95% CI: 1.33 to 1.74).
conclusionHALP score is associated with short-term mortality. Additionally, HALP score showed an incremental effect on SOFA score in predicting short-term mortality.
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