Evidence map›Paper›PMID 39925113›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2025

Favorable alterations in ventricular-arterial interactions across the menstrual cycle in healthy premenopausal women.

Ninette Shenouda, Joseph M Stock, Nicholas V Chouramanis, Zoe R Lincoln, Megan M Wenner, Julio A Chirinos, David G Edwards

Abstract readComparative Study
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Assessing health in aging male and female mice: does cardiac function dictate frailty or physical resilience?The journals of gerontology. Series A, Biological sciences and medical sciences · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ninette ShenoudaDepartment of Kinesiology and Applied Physiology, University of Delaware, Newark, Delaware, United States.ORCID 0000-0001-6505-7057
Joseph M StockDepartment of Kinesiology, East Carolina University, Greenville, North Carolina, United States.ORCID 0000-0002-9866-415X
Nicholas V ChouramanisDepartment of Kinesiology and Applied Physiology, University of Delaware, Newark, Delaware, United States.ORCID 0000-0003-0852-0708
Zoe R LincolnDepartment of Kinesiology and Applied Physiology, University of Delaware, Newark, Delaware, United States.
Megan M WennerDepartment of Kinesiology and Applied Physiology, University of Delaware, Newark, Delaware, United States.ORCID 0000-0003-0055-783X
Julio A ChirinosPerelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States.ORCID 0000-0001-9035-5670
David G EdwardsDepartment of Kinesiology and Applied Physiology, University of Delaware, Newark, Delaware, United States.ORCID 0000-0002-5098-6678

Funding

Vascular Consequences of Duchenne Muscular DystrophyP20GM113125 · NIGMS · UNIVERSITY OF DELAWARE · PI EDWARDS, DAVID G · 2016 to 2025
$23.3M
VASCULAR EFFECTS OF DIETARY SALT IN HUMANS WITH SALT-RESISTANT BPR01HL104106 · NHLBI · UNIVERSITY OF DELAWARE · PI EDWARDS, DAVID G, FARQUHAR, WILLIAM B · 2011 to 2021
$4.5M
American Heart Association (AHA) 826955HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) R01HL104106HHS | NIH | National Institute of General Medical Sciences (NIGMS) P20GM113125NIGMS NIH HHS P20 GM113125
6 · The paper itself

Abstract

Increased arterial wave reflections can increase left ventricular wasted pressure effort (WPE) and cardiovascular disease risk. Naturally menstruating women experience fluctuations in sex hormones with known cardioprotective effects. We sought to determine whether hormonal fluctuations alter arterial hemodynamics or wave reflections, and thereby WPE, or contribute to sex differences. We hypothesized that premenopausal women would have favorable wave reflection changes and reduced WPE during high- versus low-hormone cycle phases and compared with men. We tested 13 women (28 ± 7 yr) during the early follicular (EF,

Indexed as

Arterial PressureMenstrual CyclePremenopauseVentricular Function, LeftAdultEstradiolFemaleHemodynamicsHumansMaleSex FactorsVascular ResistanceYoung AdultEstradiolestradiolsex differenceswasted pressure effortwave reflectionswave separation analysis

Identifiers

PMID39925113
PMCPMC13147547

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.