Evidence map›Paper›PMID 39925630›Full record

ArticleLaryngoscope investigative otolaryngology2025

A Novel Effect of

Doğan Çakan, Zeliha Kübra Çakan, Gülderen Yılmaz, David Yeung, Gülnur Ekşi Bona

Abstract read
In one paragraph

Article in Laryngoscope investigative otolaryngology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Doğan ÇakanDepartment of Otorhinolaryngology Istanbul University-Cerrahpaşa Istanbul Türkiye.ORCID https://orcid.org/0000-0002-6283-2916
Zeliha Kübra ÇakanDivision of Oncology, Department of Internal Medicine Istanbul University-Cerrahpaşa Istanbul Türkiye.
Gülderen YılmazDepartment of Pharmaceutical Botany, Faculty of Pharmacy Ankara University Ankara Türkiye.
David YeungDepartment of Otorhinolaryngology-Head and Neck Surgery The Chinese University of Hong Kong Hong Kong China.ORCID https://orcid.org/0000-0002-3466-9322
Gülnur Ekşi BonaDepartment of Pharmaceutical Botany, Faculty of Pharmacy İstanbul University-Cerrahpaşa Istanbul Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The objective of the current study was to investigate the influence of Methods: Twenty-two healthy male Sprague-Dawley rats were included in this study and separated into two groups. A standardized NSP was created in each subject. A 0.09% saline (control group) and the 25% AT solution (study group) were delivered intranasally daily for 14 days. At the end of the experiment, the subjects were sacrificed and the septa were excised for histopathological investigation. The macroscopic closure rate of NSP, intranasal pH, counts of acute inflammatory cells, eosinophil, fibroblast, and giant cell, epithelial regeneration and degeneration, vascularization, granulation formation, collagen density, cartilage regeneration, and degeneration were examined. The obtained data were analyzed statistically. Results: The macroscopic closure rate ( Conclusion: The topically delivered AT extract may improve wound healing in an experimental NSP model. Consequently, the local application of AT might be promising to prevent the formation of NSP.

Indexed as

Alliumanimalsexperimental studynasal septal perforationplant extracts/pharmacologywound healing

Identifiers

PMID39925630
PMCPMC11806374

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.