Observational studyJournal of hypertension2025
Evaluation of Aktiia cuffless blood pressure monitor across 24-h, daytime, and night-time measurements versus ambulatory monitoring: a prospective, single-centre observational study.
Observational study in Journal of hypertension, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04548986 (Single-center Prospective Study to Validate the Performance of the Aktiia Optical Blood Pressure Monitoring), which is not on this map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Single-center Prospective Study to Validate the Performance of the Aktiia Optical Blood Pressure Monitoring (OBPM) Device at the Wrist Against Ambulatory Blood Pressure Monitoring (ABPM)
Who cites it
11 citing papers in PubMed.
- Validation of ring-type cuffless blood pressure (BP) monitoring device for detecting awake-asleep BP variations compared to ambulatory BP monitoring device.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- Validation study on cuffless ambulatory blood pressure monitoring method using bio-impedance, impedance cardiography and electrocardiography.European journal of applied physiology · 2026Article
- Disparities in Blood Pressure Measurement.Current hypertension reports · 2026Review
- Evaluation of Alysis-001 cuffless blood pressure estimation algorithm against the European Society of Hypertension awake/asleep test criteria in hypertensive patients.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- Deep learning prediction of nocturnal hypertension for patients intolerant to ambulatory blood pressure monitoring.Communications medicine · 2026Article
- A randomized crossover clinical trial comparing 24-h blood pressure measurements from two different cuffless wrist ambulatory monitors with cuffed ambulatory monitoring for translation to clinical practice: Rationale and Design of Continuum BP study.American heart journal plus : cardiology research and practice · 2026Article
- Wearable, cuffless, and portable devices for blood pressure monitoring (2015-2025): a scoping review of technologies, calibration, clinical validation, and regulatory frameworks.Frontiers in digital health · 2026Article
- Continuous assessment and research on enhanced blood pressure control - CareBP study.Frontiers in cardiovascular medicine · 2026Article
- Taking heart rate variability to the next level in sports: towards a multi-signal integration.Frontiers in sports and active living · 2026Article
- To be (IIb), or not to be (IIb) - That is the current status of cuffless blood pressure monitoring device.Clinical hypertension · 2026Review
- Cuffless Blood Pressure Measurement: Where Do We Actually Stand?Hypertension (Dallas, Tex. : 1979) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesCuffless blood pressure (BP) monitors represent an innovative approach to BP assessment, overcoming the traditional episodic nature of readings obtained from cuff-based, oscillometric modalities. Nonetheless, the comparison of these cuffless devices against their cuff-based counterparts remain debated.
methodsThis study evaluated BP readings from a cuffless, continual BP monitor (Aktiia monitor, Neuchâtel, Switzerland) and a standard 24-h ambulatory BP monitor (ABPM; Dyasis 3, Novacor, Paris, France) in 54 patients undergoing a 12-week cardiac rehabilitation program in Neuchâtel, Switzerland. Comparisons encompassed 24-h, daytime (9 a.m.-9 p.m.), and night-time (11 p.m.-7 a.m.) systolic and diastolic BP (SBP, DBP) using a 7-day average from Aktiia overlapping a 1-day average from ABPM. Nocturnal dip analysis was performed with 1-day average from Aktiia coinciding with ABPM measurements.
resultsNo significant differences emerged between the Aktiia and ABPM monitors for 24-h and daytime SBP (24-h: 2.6 ± 12.3 [-0.2, 5.4] mmHg, r = 0.57, P = 0.06; daytime: 1.2 ± 12.4 [-1.6, 4.0] mmHg, r = 0.60, P = 0.38). Night-time SBP showed more evident differences (12.5 ± 14.4 [9.3, 15.8] mmHg, r = 0.39, P < 0.001). DBP were within clinical range across 24-h and daytime (24-h: -2.9 ± 7.9 [-4.7, -1.1] mmHg, r = 0.63, P = 0.002; daytime: -3.1 ± 8.2 [-5.0, -1.3] mmHg, r = 0.64, P = 0.001), and showed significant differences for night-time (4.1 ± 8.5 [2.2, 6.0] mmHg, r = 0.57, P < 0.001). The concordance rate with ABPM's nocturnal dip was 79% for 1-day average from Aktiia.
conclusionsThese results demonstrate that the Aktiia monitor yields BP measurements consistent with an ABPM monitor despite some systematic differences during night-time readings. The Aktiia monitor holds potential for future use in continual BP monitoring. CLINICAL
trial registrationNCT04548986. URL: https://clinicaltrials.gov/study/NCT04548986?tab=results.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.