Evidence map›Paper›PMID 39928634›Full record

ArticlePloS one2025

Implementation and first report of the Brazilian Kidney Biopsy Registry.

Irene L Noronha, Rodrigo José Ramalho, Claudia Maria Costa de Oliveira, Marilia Bahiense-Oliveira, Fabricio Augusto Marques Barbosa, Jose de Resende Barros Neto, Ronny Mitsuoka, Osvaldo Merege Vieira-Neto, Precil Diego Miranda de Menezes Neves, Brazilian Kidney Biopsy Registry Working Group

Abstract read
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Irene L NoronhaClinical Nephrology Department of the Brazilian Society of Nephrology, São Paulo, Brazil.
Rodrigo José RamalhoClinical Nephrology Department of the Brazilian Society of Nephrology, São Paulo, Brazil.
Claudia Maria Costa de OliveiraClinical Nephrology Department of the Brazilian Society of Nephrology, São Paulo, Brazil.
Marilia Bahiense-OliveiraClinical Nephrology Department of the Brazilian Society of Nephrology, São Paulo, Brazil.
Fabricio Augusto Marques BarbosaClinical Nephrology Department of the Brazilian Society of Nephrology, São Paulo, Brazil.
Jose de Resende Barros NetoClinical Nephrology Department of the Brazilian Society of Nephrology, São Paulo, Brazil.
Ronny MitsuokaPostgraduate, Radiology Institute Hospital das Clinicas, University of São Paulo Medical School, São Paulo, Brazil.
Osvaldo Merege Vieira-NetoNephrology Discipline, Ribeirão Preto Medical School-University of São Paulo, Ribeirão Preto, Brazil.ORCID https://orcid.org/0000-0002-9134-4583
Precil Diego Miranda de Menezes NevesClinical Nephrology Department of the Brazilian Society of Nephrology, São Paulo, Brazil.ORCID https://orcid.org/0000-0003-1089-6763
Brazilian Kidney Biopsy Registry Working Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundKidney biopsy registries are valuable tools for guiding clinical practice and developing health policies. In 2021, the Brazilian Society of Nephrology (SBN) created the Brazilian Kidney Biopsy Registry (BKBR). This is the first BKBR report, presenting patient data from 2021.

methodsBKBR is a web-based platform hosted on the BSN website, which contains patient demographics, clinical data, frequency, and distribution of histologic diagnosis of Brazilian adult native kidney biopsies.

resultsOf the 1012 cases registered in 2021, 954 cases were evaluated after excluding pediatric and kidney transplant cases. Twenty-one centers enrolled patients, with representation from all Brazilian regions. There was a slight predominance of females (52.6%), a mean age of 44.7 ± 16 years, and 13.6% of patients were >65 years old. The main indication for kidney biopsy was renal dysfunction (56%) and nephrotic syndrome (41.4%), respectively. At the time of the biopsy, 47.9% of the patients were hypertensive and 15.2% were diabetic. Although 66.2% of patients had eGFR ≤60ml/min/1.73m2 upon biopsy, the majority (60.2%) had mild interstitial fibrosis and tubular atrophy. The most frequent diagnosis in the BKBR was glomerular disease (74.8%). Lupus nephritis was the most frequent diagnosis of glomerular disease (22.6%), followed by IgA nephropathy (13%) and focal segmental glomerulosclerosis (12.2%).

conclusionThis is the first report of a Nationwide registry of kidney biopsies in Brazil. This data provides pivotal information about the kidney disease profile in this country with continental dimensions.

Indexed as

KidneyKidney DiseasesRegistriesAdultAgedBiopsyBrazilFemaleHumansMaleMiddle AgedYoung Adult

Identifiers

PMID39928634
PMCPMC11809849

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.