Evidence map›Paper›PMID 39929921›Full record

ArticleScientific reports2025

Developing a nomogram for risk prediction of the low T3 syndrome.

Xiao-Li Feng, Hui-Min Chen, Liu-Juan Yin, Jin Chen, Li-Liang Chen

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xiao-Li FengDepartment of Geriatric Medicine, Anqing Municipal Hospital/Anqing Medical Center of Anhui Medical University, Anqing, China.
Hui-Min ChenDepartment of Geriatric Medicine, Anqing Municipal Hospital/Anqing Medical Center of Anhui Medical University, Anqing, China.
Liu-Juan YinDepartment of Geriatric Medicine, Anqing Municipal Hospital/Anqing Medical Center of Anhui Medical University, Anqing, China.
Jin ChenDepartment of Endocrinology and Metabolism, Changhai Hospital, Second Military Medical University/Naval Medical University, Shanghai, China. chenjin@smmu.edu.cn.
Li-Liang ChenDepartment of Geriatric Medicine, Anqing Municipal Hospital/Anqing Medical Center of Anhui Medical University, Anqing, China. chenliliangwy@163.com.

Funding

Wannan Medical College University-level Research Project JXYY202240
6 · The paper itself

Abstract

The objective of this study is to establish a nomogram for predicting low triiodothyronine syndrome (LTS), and clarify the risk factors of LTS. In this study, 109 LTS patients and 331 non-LTS patients were included as the subjects. The general biochemical information of the subjects was collected, and the relevant factors of LTS were evaluated. Concordance index (C-index), Calibration plot, Hosmer-Lemeshow test (H-L test), and Receiver Operating Characteristic (ROC) curve were used to assess the nomogram model. The results of the multiple logistic regression analysis showed that the chronic heart failure (CHF) (OR: 1.978, 95% CI: 1.006-3.892), interleukin-6 (IL-6) (OR: 2.018, 95%CI: 1.043-3.901), infection (OR: 2.136, 95%CI: 1.154-3.955), C-reactive protein (CRP) (OR: 2.720, 95%CI: 1.311-5.641), and N-terminal pro-B-type natriuretic peptide (NT-proBNP) (OR: 3.121, 95%CI: 1.691-5.759) might be the relevant independent risk factors for LTS (P < 0.05), while serum albumin (Alb) might be a protective factor (P < 0.05). All the significant predictors were combined into a predictive nomogram, and the obtained C-index was 0.867 (95% CI: 0.824-0.910). The calibration plot showed good performance of the nomogram, and the predictive model passed H-L test (χ

Indexed as

Euthyroid Sick SyndromesNomogramsTriiodothyronineAdultAgedBiomarkersC-Reactive ProteinFemaleHeart FailureHumansInterleukin-6MaleMiddle AgedNatriuretic Peptide, BrainPeptide FragmentsRisk FactorsBiomarkersC-Reactive ProteinInterleukin-6Natriuretic Peptide, BrainPeptide Fragmentspro-brain natriuretic peptide (1-76)TriiodothyronineNomogramPrediction modelRisk factorsTriiodothyronine syndrome

Identifiers

PMID39929921
PMCPMC11811073

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.