Evidence map›Paper›PMID 39930404›Full record

ArticleBMC oral health2025

Dentofacial deformities as independent predictors of sleep disorders: a cross-sectional study of young adults.

Yuanyuan Li, Yun Lu, Xiaofen Liu, Lixiang Liu, Wenyi Mei, Wei Zhang, Bingjiao Zhao, Yuehua Liu

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Article in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Yuanyuan Li *Department of Pediatric Dentistry, Shanghai Stomatological Hospital & School of Stomatology, Fudan University, Shanghai, China.
Yun Lu *Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases, Fudan University, Shanghai, China.
Xiaofen LiuDepartment of nursing, Shanghai Stomatological Hospital, Fudan University, Shanghai, China.
Lixiang LiuCampus Hospital of Fudan University, Shanghai, China.
Wenyi MeiDepartment of nursing, Shanghai Stomatological Hospital, Fudan University, Shanghai, China.
Wei ZhangBiomedical informatics & statistics center, School of Public Health, Fudan University, Shanghai, China.
Bingjiao ZhaoDepartment of Orthodontics, Shanghai Stomatological Hospital & School of Stomatology, Fudan University, Shanghai, China. joyce_zhao_ortho@fudan.edu.cn.
Yuehua LiuShanghai Key Laboratory of Craniomaxillofacial Development and Diseases, Fudan University, Shanghai, China. liuyuehua@fudan.edu.cn.

Funding

Nation Key Clinical Program on Orthodontics GJLCZDZK2023-01Shanghai Municipal Health Commission 202340147, 2023ZZ02009, 202240182 and 202340266Shanghai Shenkang Hospital Development Center SHDC2020CR2043B
6 · The paper itself

Abstract

backgroundSleep disorders (SDs), a public health concern, can lead to critical physiological conditions, and are associated with mental and behavior problems such as psychosocial stress, smoking, alcohol consumption, etc. This study aimed to investigate the cross-sectional associations between dentofacial deformities and sleep quality in young adults in China.

methodsData were collected from 2,479 young adults (aged 17-25 years) enrolled at Fudan University across various regions of China. Participants completed a self-reported questionnaire that included general information and the Pittsburgh Sleep Quality Index (PSQI) under standardized guidance. Dentofacial characteristics were examined by experienced orthodontists. Data analysis employed one-way ANOVA, student's t-test, chi-square tests, and multivariable logistic regression models.

resultsThe study revealed a median PSQI score of 5.92 ± 1.66, with 16.3% of participants classified as SDs. Higher PSQI scores were reported by females, underweight individuals, and participants from southern regions. Among the subjects, 44.36% exhibited protruding profiles, 6.86% had concave profiles, and various dentofacial abnormalities were prevalent. Logistic regression analysis identified protruding lateral profiles (OR 1.93, 95% CI 1.18-3.16, p = 0.008) and anterior crossbite (OR 1.44, 95% CI 1.01-2.04, p = 0.043) as significant risk factors for SDs. Additionally, reduced anterior overbite was associated with a higher prevalence of SDs, while deep overbite acted as a protective factor. Moderate overbite demonstrated statistical significance (OR 0.51, 95% CI 0.35-0.76, p = 0.001).

conclusionThese findings suggest a significant association between dentofacial characteristics and sleep quality in young adults. Protruding facial profiles and anterior crossbites were identified as independent predictors for SDs. These findings underscore the importance of screening for SDs in individuals with dentofacial deformities and highlight the potential benefits of early correction of such dentofacial abnormalities to reduce the risk of SDs in adulthood.

Indexed as

Dentofacial DeformitiesSleep Wake DisordersAdolescentAdultChinaCross-Sectional StudiesFemaleHumansMaleRisk FactorsSleep QualitySurveys and QuestionnairesYoung AdultDentofacial deformitiesPittsburgh sleep quality indexRisk factorsSleep disordersYoung adults

Identifiers

PMID39930404
PMCPMC11809106

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.