Evidence map›Paper›PMID 39930954›Full record

Observational studyJournal of cardiovascular electrophysiology2025

The Atrial Fibrillation Registry (The FLOW-AF Registry): Insights From the United Arab Emirates-Patient Characteristics, Treatment, and One-Year Outcomes.

Moutaz El Kadri, Khalid AlMuti, Amrish Agrawal, Nooshin Bazargani, Mohamed Fathy Soliman Gamaleldin, Haytham Mohamed Ahmed, Omneya Hassanain, Natasha Khalife, Ghazi Radaideh, Mohamed Magdy and 1 more

Abstract readObservational StudyMulticenter Study
In one paragraph

Observational study in Journal of cardiovascular electrophysiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Women's cardiovascular health in 2025:Saudi medical journal · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Moutaz El KadriSheikh Khalifa Medical City, Abu Dhabi, United Arab Emirates.
Khalid AlMutiCleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.
Amrish AgrawalFujairah Hospital, EHS, Fujairah, United Arab Emirates.
Nooshin BazarganiDubai Hospital, Dubai, United Arab Emirates.
Mohamed Fathy Soliman GamaleldinPfizer Gulf, Dubai, United Arab Emirates.
Haytham Mohamed AhmedPfizer Gulf, Dubai, United Arab Emirates.ORCID 0000-0002-2883-3317
Omneya HassanainIQVIA, Real-World Evidence, Dubai, United Arab Emirates.
Natasha KhalifeIQVIA, Real-World Evidence, Dubai, United Arab Emirates.
Ghazi RadaidehRashid Hospital, Dubai, United Arab Emirates.
Mohamed MagdyAl Qassimi Hospital, Sharjah, United Arab Emirates.
Wael A AlmahmeedCleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.ORCID 0000-0003-0312-9910

Funding

The study was sponsored by Pfizer.
6 · The paper itself

Abstract

backgroundThe epidemiological landscape and treatment efficacy of atrial fibrillation (AF) in the Middle East, notably in the United Arab Emirates (UAE), remain under-explored, presenting a distinct demographic and clinical pattern compared to Western populations. The FLOW-AF Registry aimed to bridge this knowledge gap by examining the characteristics, treatment patterns, clinical outcomes, and healthcare resource utilization (HCRU) of newly diagnosed non-valvular atrial fibrillation (NVAF) patients in the UAE, contributing to the scant literature on NVAF management in the region.

methodsThis multicenter, prospective observational study enrolled patients diagnosed with NVAF across six sites in the UAE. Data were collected on demographics, medical history, treatment decisions, clinical outcomes, and HCRU over a 12-month observation period.

resultsA total of 198 patients were enrolled, with a mean age of 63.44 years. Mean CHA₂DS₂-VASc and HAS-BLED scores at baseline were 2.95 and 1.76, respectively. Most patients (55.77%) were prescribed non-vitamin K antagonist oral anticoagulants (NOACs). One-year incidence rates for major clinical events were 6.7% for all-cause mortality, 2.8% for bleeding complications, and 0.6% for myocardial infarction. No strokes were reported during the study period.

conclusionThe FLOW-AF Registry provides valuable insights into NVAF management in the UAE, demonstrating a distinct patient profile and a preference for NOACs. The NVAF cohort in the UAE was characterized by a younger demographic with lower risk scores and lower rate of clinical events relative to global counterparts. The findings underscore the evolving approach to AF management in the UAE, suggestive of a shift towards NOAC use but also highlights the need for ongoing research to fully understand long-term outcomes and validate current treatment paradigms in the UAE.

Indexed as

AnticoagulantsAtrial FibrillationStrokeAgedFemaleHumansIncidenceMaleMiddle AgedProspective StudiesRegistriesRisk FactorsTime FactorsTreatment OutcomeUnited Arab EmiratesAnticoagulantsclinical outcomeshealthcare resource utilizationnon‐valvular atrial fibrillationpatient characteristicstreatment patternsUAE

Identifiers

PMID39930954
PMCPMC11984346

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.