Evidence map›Paper›PMID 39931355›Full record

ReviewAsian journal of pharmaceutical sciences2025

Recent advances in zeolitic imidazolate frameworks as drug delivery systems for cancer therapy.

Yuhan Wang, Yixin Tang, Lei Guo, Xi Yang, Shanli Wu, Ying Yue, Caina Xu

Abstract readReview
In one paragraph

Review in Asian journal of pharmaceutical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yuhan WangDepartment of Biochemistry, College of Basic Medical Sciences, Jilin University, Changchun 130021, China.
Yixin TangDepartment of Biochemistry, College of Basic Medical Sciences, Jilin University, Changchun 130021, China.
Lei GuoDepartment of Biochemistry, College of Basic Medical Sciences, Jilin University, Changchun 130021, China.
Xi YangDepartment of Biochemistry, College of Basic Medical Sciences, Jilin University, Changchun 130021, China.
Shanli WuDepartment of Biochemistry, College of Basic Medical Sciences, Jilin University, Changchun 130021, China.
Ying YueDepartment of Gynecological Oncology, The First Hospital of Jilin University, Changchun 130021, China.
Caina XuDepartment of Biochemistry, College of Basic Medical Sciences, Jilin University, Changchun 130021, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biological nanotechnologies based on functional nanoplatforms have synergistically catalyzed the emergence of cancer therapies. As a subtype of metal-organic frameworks (MOFs), zeolitic imidazolate frameworks (ZIFs) have exploded in popularity in the field of biomaterials as excellent protective materials with the advantages of conformational flexibility, thermal and chemical stability, and functional controllability. With these superior properties, the applications of ZIF-based materials in combination with various therapies for cancer treatment have grown rapidly in recent years, showing remarkable achievements and great potential. This review elucidates the recent advancements in the use of ZIFs as drug delivery agents for cancer therapy. The structures, synthesis methods, properties, and various modifiers of ZIFs used in oncotherapy are presented. Recent advances in the application of ZIF-based nanoparticles as single or combination tumor treatments are reviewed. Furthermore, the future prospects, potential limitations, and challenges of the application of ZIF-based nanomaterials in cancer treatment are discussed. We except to fully explore the potential of ZIF-based materials to present a clear outline for their application as an effective cancer treatment to help them achieve early clinical application.

Indexed as

Cancer treatmentDrug deliveryMetal-organic frameworks (MOFs)Zeolitic imidazolate frameworks (ZIF-8)ZIF-based nanoparticles

Identifiers

PMID39931355
PMCPMC11808527

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.