Evidence map›Paper›PMID 39933901›Full record

ArticleBiomolecules & therapeutics2025

Daurisoline Inhibits Progression of Triple-Negative Breast Cancer by Regulating the γ-Secretase/Notch Axis.

Xiangyi Zhan, Xiaoyong Chen, Mei Feng, Kuo Yao, Kefan Yang, Hui Jia

Abstract read
In one paragraph

Article in Biomolecules & therapeutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiangyi ZhanSchool of Traditional Chinese Medicine, Shenyang Medical College, Shenyang 110034, China.
Xiaoyong ChenCollege of Life Science and Engineering, Northwest Minzu University, Lanzhou 730030, China.
Mei FengDepartment of Pathology and Pathophysiology, School of Basic Medical Sciences, Shenyang Medical College, Shenyang 110034, China.
Kuo YaoDepartment of Pathology and Pathophysiology, School of Basic Medical Sciences, Shenyang Medical College, Shenyang 110034, China.
Kefan YangDepartment of Pathology and Pathophysiology, School of Basic Medical Sciences, Shenyang Medical College, Shenyang 110034, China.
Hui JiaSchool of Traditional Chinese Medicine, Shenyang Medical College, Shenyang 110034, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Triple-negative breast cancer (TNBC) is a subtype of breast cancer that is challenging to treat and lacks targeted therapeutic drugs in the clinic. Natural active ingredients provide promising opportunities for discovering and developing targeted therapies for TNBC. This study investigated the effects of daurisoline on TNBC and elucidated its potential mechanisms. Using network pharmacology, a correlation was identified between daurisoline, derived from

Indexed as

DaurisolineDibenzylisoquinoline alkaloidRhizoma menispermi-Secretase/Notch axisTriple-negative breast cancerγ

Identifiers

PMID39933901
PMCPMC11893495

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.