ArticleMikrochimica acta2025
N-Doped carbon quantum dot-based ratiometric fluorescent nanosensor platforms for detection of gastric cancer-associated Helicobacter pylori genes.
Article in Mikrochimica acta, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Article
- Advances in Carbon Dot-Based Optical (Bio)Sensors for Contaminant Detection in Wastewater-Based Epidemiology.Sensors (Basel, Switzerland) · 2026Review
- A Facile Ratiometric Fluorescent Biosensor Using Blue-emitting Carbon Dots and Acriflavine for Quantitative Detection of DNA.Journal of fluorescence · 2025Article
- Dual-emission nitrogen-doped carbon dots for ratiometric and smartphone-based detection of levofloxacin.RSC advances · 2025Article
- Holmium(III)-Carbon Nanodots Hybrid for Fluorescent Quenching Effect in the Oxalate Detection (CACS omega · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Carbon quantum dot (CQD)-based fluorescent nanosensor platforms were developed using gastric cancer-associated Heliobacter pylori (H. pylori) genes. N-doped CQDs were synthesized using two different organic acids (citric acid and malic acid) and ethylenediamine by the microwave method. The photophysical and photochemical properties of the synthesized CQDs were investigated by ultraviolet-visible, fluorescence, and Fourier-transform infrared spectra. The surface of the synthesized N-doped CQDs was conjugated with single-stranded DNA (ssDNA), which is specific for gastric cancer. Ethidium bromide, a selective dye, shows enhanced fluorescence intensity upon intercalating with DNA. In the blue-emissive CQD-ssDNA nanoprobe system, the fluorescence intensity was quenched by ethidium bromide due to Förster resonance energy transfer (FRET) processes. When complementary ssDNA was introduced, the ethidium bromide strongly intercalated with the newly formed double-stranded DNA, shifting to a red emission. Using this ratiometric system, the detection method was improved for gastric cancer-associated genes, achieving a limit of detection (LOD) of 0.098 µM, within a concentration range 1.30 to 11.49 µM. Spike and recovery tests were also conducted to evaluate the precision of the presented method in synthetic saliva solutions, with recoveries ranging from 93.06% to 101.85% The performance of the nanosensors was compared using two different synthesized CQDs.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.