SynthesisBMC cancer2025
Prognostic role of geriatric nutritional risk index (GNRI) and controlling nutritional status (CONUT) on outcomes in patients with head and neck cancer: a systematic review and meta-analysis.
Synthesis in BMC cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Prognostic value of the Controlling Nutritional Status (CONUT) score in cancer: an umbrella review of systematic reviews and meta-analyses.Frontiers in nutrition · 2026Pooled it
- Prognostic value of Prognostic Nutritional Index in cancer: an umbrella review of systematic review and meta-analysis.Frontiers in nutrition · 2025Pooled it
- [Comparison of preoperative nutritional scoring systems for predicting survival in upper tract urothelial carcinoma].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2026Article
- Mapping Nutritional Assessment and Management in Oncology: Challenges and Perspectives from a Regional Survey.Nutrients · 2026Article
- Nutritional Indices Are Associated with Mortality in the Elderly Patients Undergoing Left Atrial Appendage Occlusion: A Comparative Study of CONUT, GNRI, and PNI.Journal of cardiovascular development and disease · 2026Article
- A nutritional risk index-based nomogram for predicting prognosis and identifying induction chemotherapy beneficiaries in nasopharyngeal carcinoma.Scientific reports · 2026Article
- Diagnostic value of geriatric nutritional risk index and phase angle for malnutrition in patients with COPD: a retrospective cohort study.Frontiers in nutrition · 2026Article
- Prognostic significance of immune-inflammatory and nutritional indicators in locoregionally advanced nasopharyngeal carcinoma.Frontiers in immunology · 2026Article
- Real-World Outcomes of Treatment Approaches and the Impact of Systemic Inflammation Markers on Survival in Patients with Locally Advanced and Metastatic Laryngeal Cancer.Journal of clinical medicine · 2025Article
- The Effect of Diabetes Medication on the Scores of the GNRI and CONUT Nutritional Indices: Cross-Sectional and Longitudinal Retrospective Studies.Clinical and translational science · 2025Article
- Article
- Insights into the Prognostic Efficacy of the Geriatric Nutritional Risk Index for Nasopharyngeal Carcinoma in the Era of Volumetric Modulated Arc Therapy: A Nomogram for Predicting Long-Term Survival Outcomes.Current oncology (Toronto, Ont.) · 2025Article
- Prognostic Role of Inflammatory and Nutritional Indices in NSCLC Patients Treated with Immune Checkpoint Inhibitors: Retrospective, Multicenter, Turkish Oncology Group Study of Overall and Elderly Populations.Medicina (Kaunas, Lithuania) · 2025Article
- Significance of the geriatric nutritional risk index and body composition as prognostic indicators in gastric cancer patients.Frontiers in oncology · 2025Article
- Nutritional status affects inflammatory responses and exacerbates the severity of pulmonary tuberculosis.Frontiers in cellular and infection microbiology · 2025Article
- Tumour necrosis factor-Frontiers in nutrition · 2025Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMalnutrition is a common comorbidity in patients with head and neck cancer (HNC), significantly impacting survival rates. The Geriatric Nutritional Risk Index (GNRI) and the Controlling Nutritional Status (CONUT) score are tools used to assess the nutritional status, yet their prognostic value in HNC remains to be fully established.
methodsWe performed a systematic review and meta-analysis, adhering to PRISMA guidelines, to evaluate the prognostic significance of GNRI and CONUT on survival outcomes in patients with HNC. Relevant studies up to March 2024 were identified through comprehensive searches of PubMed, EMBASE, and Cochrane CENTRAL databases. The quality of each included study was assessed using the Newcastle-Ottawa Scale.
resultsSeventeen studies were included, encompassing a total of 3,816 patients with HNC. Our findings reveal that a lower GNRI is consistently associated with poor overall survival (OS, adjusted hazard ratio [aHR]: 3.9, 95% confidence interval [CI]: 2.47-6.14) and progression-free survival (PFS, aHR: 1.76, 95% CI: 1.41-2.21), demonstrating its utility as a prognostic indicator. However, CONUT scores revealed no significant differences in OS (aHR: 1.65, 95% CI: 0.94-2.91) or PFS (aHR: 1.43, 95% CI: 0.68-3.02).
conclusionGNRI appears to be a reliable prognostic tool for predicting poorer survival outcomes in HNC patients, underscoring the importance of nutritional assessments in this population. Further research is needed to clarify the prognostic value of the CONUT score, which exhibited less consistent results.
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