Evidence map›Paper›PMID 39935889›Full record

ArticleAlzheimer's & dementia (Amsterdam, Netherlands)

Cognitive markers for the distinction between asymptomatic and prodromal Alzheimer's disease in Down syndrome: Correlations with volumetric brain changes.

Javier García-Alba, Elisa M Molanes-López, Pilar Zuluaga, Cristina Bell-Fenellos, Lucía Vaquero, Eva Alfayate, Felipe García, Gloria Mateo, Fernando Modenhauer, José M Galván-Román and 2 more

Abstract read
In one paragraph

Article in Alzheimer's & dementia (Amsterdam, Netherlands). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Javier García-AlbaDepartment of Psychology in Education and Research Complutense University of Madrid Madrid Spain.ORCID https://orcid.org/0000-0002-3342-6572
Elisa M Molanes-LópezDepartment of Statistics and Operational Research Complutense University of Madrid Madrid Spain.
Pilar ZuluagaDepartment of Statistics and Operational Research Complutense University of Madrid Madrid Spain.
Cristina Bell-FenellosDepartment of Psychology in Education and Research Complutense University of Madrid Madrid Spain.
Lucía VaqueroDepartment of Experimental Psychology, Cognitive Processes and Speech Therapy; & Research Group in Digital Culture and Social Movements Complutense University of Madrid Madrid Spain.
Eva AlfayateNeuroimaging, Reina Sofia Alzheimer Center CIEN Foundation, ISCIII Madrid Spain.
Felipe GarcíaNeuroimaging, Reina Sofia Alzheimer Center CIEN Foundation, ISCIII Madrid Spain.
Gloria MateoDepartment of Internal Medicine La Princesa University Hospital/La Princesa Biomedical Research Institute Madrid Spain.
Fernando ModenhauerDepartment of Internal Medicine La Princesa University Hospital/La Princesa Biomedical Research Institute Madrid Spain.
José M Galván-RománDepartment of Internal Medicine La Princesa University Hospital/La Princesa Biomedical Research Institute Madrid Spain.
Ricardo BajoInstitute of Applied Magnetism Complutense University of Madrid Madrid Spain.
Alberto FernándezDepartment of Legal Medicine Psychiatry and Pathology, Complutense University of Madrid Madrid Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionMotivated by the difficulties in detecting cognitive deterioration in the context of Down syndrome (DS), we aimed to identify markers of prodromal Alzheimer's disease (AD) in this population.

methodsSixty-two participants with DS (age > 45) distributed in three groups (asymptomatic [A

resultsAlthough temporal orientation showed significant differences among groups, only a predictive diagnostic model based on verbal short-term memory tasks (relying on "cued" recall) allowed the correct classification of 88.5% of A DISCUSSION: Neuropsychological results showed that P

Indexed as

Alzheimer's diseasecognitive impairmentDown syndromemagnetic resonance imagingneuropsychological assessmentprodromal Alzheimer's disease

Identifiers

PMID39935889
PMCPMC11812121

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.