Evidence map›Paper›PMID 39937369›Full record

ArticleLa Radiologia medica2025

Baseline

Silvia Taralli, Armando Orlandi, Pia Clara Pafundi, Valeria Tempesta, Alba Di Leone, Letizia Pontolillo, Lorenzo Scardina, Margherita Lorusso, Ida Paris, Maria Lucia Calcagni

Abstract read
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In one paragraph

Article in La Radiologia medica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Silvia TaralliNuclear Medicine Unit, Diagnostic Imaging and Radiation Oncology Department, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo Francesco Vito 1, 00168, Rome, Italy. silvia.taralli@policlinicogemelli.it.ORCID http://orcid.org/0000-0002-1715-9953
Armando OrlandiMedical Oncology Unit, Comprehensive Cancer Center, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Pia Clara PafundiEpidemiology and Biostatistics Research Core Facility, Gemelli Generator, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.
Valeria TempestaNuclear Medicine Unit, Diagnostic Imaging and Radiation Oncology Department, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo Francesco Vito 1, 00168, Rome, Italy.
Alba Di LeoneBreast Center Unit, Health Sciences of Women, Children and Public Health Department, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Letizia PontolilloMedical Oncology Unit, Comprehensive Cancer Center, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Lorenzo ScardinaBreast Center Unit, Health Sciences of Women, Children and Public Health Department, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Margherita LorussoNuclear Medicine Unit, Diagnostic Imaging and Radiation Oncology Department, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo Francesco Vito 1, 00168, Rome, Italy.
Ida ParisDivision of Gynecologic Oncology, Department of Women and Child Health and Public Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Maria Lucia CalcagniNuclear Medicine Unit, Diagnostic Imaging and Radiation Oncology Department, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo Francesco Vito 1, 00168, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate metabolic parameters from baseline MATERIALS AND

methodsFrom 142 LABC in 137 patients (bilateral-synchronous BC: 5/137), the following parameters from baseline (pre-treatment)

results74/142 tumors were "Luminal A/B HER2-", 44/142 "Luminal B HER2+/HER2+", 24/142 TNBC; pCR after NAC occurred in 26/142 tumors (18.3%) and disease recurrence at follow-up (45 ± 18.1 months) in 25/127 assessable patients (19.7%). Significant or suggestive predictors of NAC response, in Luminal A/B HER2-: lower spleen SUVmax and patients' age (OR 0.06; 0.93) for pCR; lower TLRmax, TLRmean and BLRmax (OR 1.33; 1.22; and 26.42) for residual disease. Significant negative RFS predictors: higher SUVmax, SUVmean, SUVpeak (HR 1.10; 1.15; 1.11), TLRmax and TLRmean (HR 1.02; 1.00), MTV and TLG (HR 1.32; 1.26) in Luminal A/B HER2-; higher spleen SUVmax, PET-positive nodes' number and patients' age (HR 6.24; 1.20; 1.08) in Luminal B HER2+/HER2+.

conclusionPrimary tumor and lymphoid organs parameters at baseline

Indexed as

Breast NeoplasmsFluorodeoxyglucose F18Neoadjuvant TherapyPositron Emission Tomography Computed TomographyAdultAgedChemotherapy, AdjuvantFemaleHumansMiddle AgedPredictive Value of TestsPrognosisRadiopharmaceuticalsRetrospective StudiesTreatment OutcomeFluorodeoxyglucose F18Radiopharmaceuticals18F-fluoro-deoxy-glucoseBreast cancerNeoadjuvant chemotherapyPathological responsePET/CTPrognosis

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.