ArticleCurrent biology : CB2025
Transformations in prefrontal ensemble activity underlying rapid threat avoidance learning.
Article in Current biology : CB, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- High-fat diet exposure, internal state, and reward value influence decision making during motivational conflict.Neurobiology of stress · 2026Article
- A shared ensemble in the prelimbic cortex links impulsivity and anxiety-like behavior.bioRxiv : the preprint server for biology · 2025Article
- Dopaminergic projections to the prefrontal cortex are critical for rapid threat avoidance learning.Current biology : CB · 2025Article
- Directed cell-type recruitment during consolidation of a remote memory.bioRxiv : the preprint server for biology · 2025Article
- Modifying the platform-mediated avoidance task: A new protocol to study active avoidance within a social context in rats.PloS one · 2025Article
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Authors and funding
6 authors.
Funding
Abstract
To survive, animals must rapidly learn to avoid aversive outcomes by predicting threats and taking preemptive actions to avoid them. Often, this involves identifying locations that are safe in the context of specific, impending threats and remaining in those locations until the threat passes. Thus, animals quickly learn how threat-predicting cues alter the implications of entering or leaving a safe location. The prelimbic subregion (PL) of the medial prefrontal cortex (mPFC) integrates learned associations to influence threat avoidance strategies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.