ArticleNature2025
Macrophages protect against sensory axon loss in peripheral neuropathy.
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Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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34citing papers in PubMed
–field-weighted citation impact
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
34 citing papers in PubMed.
- Artificial intelligence-assisted design of self-assembling peptide hydrogels for neural regeneration: Principles and opportunities.Bioactive materials · 2027Review
- Single-cell and single-nucleus transcriptomics of the dorsal root ganglion in neuropathic pain: cell-state remodeling and translational prospects.Journal of translational medicine · 2026Review
- Diabetes and the Metabolic Syndrome as Drivers of Neurodegeneration: Convergent Mechanisms Linking Peripheral Neuropathy and Dementia.Annals of neurology · 2026Review
- Targeting GCell reports. Medicine · 2026Article
- Inflammatory neuropathy in mouse and primate models of colorectal cancer.Nature communications · 2026Article
- Review
- Tissue-Resident Macrophage PIEZO1 Transduces Mechanical Stress into Inflammatory Pain in Acute Gout.Neuroscience bulletin · 2026Article
- Skin-resident Langerhans cells drive neuropathic pain via chemokine-dependent neuron-immune communication.The Journal of clinical investigation · 2026Article
- Smart immunomodulatory polysaccharide hydrogels promote diabetic bone regeneration by regulating the inflammation-angiogenesis-osteogenesis axis.Materials today. Bio · 2026Article
- Otilonium bromide ameliorates paclitaxel-induced peripheral neuropathy by targeting phosphatase PPM1A.Journal of neuroinflammation · 2026Article
- Neuroimmune Dynamics in Diseases of the Arterial Wall: Mechanistic Foundations and Translational Prospects.Current atherosclerosis reports · 2026Review
- 3D-bioprinted mesenchymal stem cell-derived exosomes reprogram macrophages via PI3K/AKT to accelerate nerve regeneration.Journal of translational medicine · 2026Article
- Satellite Glial Cells Control Sensory Neuron Excitability via the Release of Fibulin-2.bioRxiv : the preprint server for biology · 2026Article
- Peripheral nerve injury reduces macrophage efferocytosis to facilitate neuropathic pain.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Preservation of Nociceptor Intraepidermal Nerve Fibres in Diabetic Neuropathic Pain.Journal of diabetes research · 2026Article
- Behavioral assessment of pain in rodents: advances from evoked responses to spontaneous states and multimodal approaches.Frontiers in pain research (Lausanne, Switzerland) · 2026Review
- Dietary monounsaturated fatty acids reduce nerve inflammation and improve nerve function in murine models of obesity.Frontiers in immunology · 2026Article
- RYGB induces vagal sensory neuropathy characterized by altered Glp1r expression and enhanced exendin-4 responsiveness in male mice.American journal of physiology. Endocrinology and metabolism · 2026Article
- The pivotal role of immunometabolism in diabetic neuropathy and its potential therapeutic strategies.Frontiers in endocrinology · 2026Review
- Diabetic neuropathy's immune-metabolic network: mechanistic complexity, therapeutic challenges, and the path forward.Frontiers in immunology · 2026Review
Corrections and comments
- Update of
Authors and funding
13 authors.
Sara HakimDepartment of Neurobiology, Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-0091-1221
Aakanksha JainF.M. Kirby Neurobiology Center, Boston Children's Hospital, Boston, MA, USA.ORCID 0000-0001-9602-4987
Stuart S AdamsonDepartment of Endocrinology, Boston Children's Hospital, Boston, MA, USA.
Veselina PetrovaF.M. Kirby Neurobiology Center, Boston Children's Hospital, Boston, MA, USA.ORCID 0000-0002-5593-0198
Jonathan IndajangF.M. Kirby Neurobiology Center, Boston Children's Hospital, Boston, MA, USA.
Hyoung Woo KimF.M. Kirby Neurobiology Center, Boston Children's Hospital, Boston, MA, USA.ORCID 0000-0002-5487-0146
Riki KawaguchiDepartment of Neurology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Qing WangCenter for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, CA, USA.
Elif S DuranF.M. Kirby Neurobiology Center, Boston Children's Hospital, Boston, MA, USA.ORCID 0009-0006-9530-4526
Drew NelsonF.M. Kirby Neurobiology Center, Boston Children's Hospital, Boston, MA, USA.
Caitlin A GreeneF.M. Kirby Neurobiology Center, Boston Children's Hospital, Boston, MA, USA.
Jenae RasmussenF.M. Kirby Neurobiology Center, Boston Children's Hospital, Boston, MA, USA.
Clifford J WoolfDepartment of Neurobiology, Harvard Medical School, Boston, MA, USA. Clifford.Woolf@childrens.harvard.edu.ORCID 0000-0002-6636-3897
Funding
Unravelling Mechanisms and Novel Therapeutic Targets for Peripheral Neuropathy and Neuropathic Pain (Diversity Supplement)R35NS105076 · NINDS · BOSTON CHILDREN'S HOSPITAL · PI WOOLF, CLIFFORD J · 2018 to 2025
$9.5MThe Role of Sciatic Nerve Inflammation in Diabetic NeuropathyF31NS127357 · NINDS · HARVARD MEDICAL SCHOOL · PI HAKIM, SARA · 2022 to 2023
$76kNINDS NIH HHS F31 NS127357NINDS NIH HHS R35 NS105076
Abstract
Peripheral neuropathy is a common complication of type 2 diabetes, which is strongly associated with obesity
Indexed as
AxonsMacrophagesPeripheral Nervous System DiseasesSensory Receptor CellsAnimalsDiabetes Mellitus, Type 2Diabetic NeuropathiesDiet, High-FatFemaleFructoseGalectin 3MaleMiceObesityPrediabetic StateReceptors, CCR2Ccr2 protein, mouseFructoseGalectin 3Receptors, CCR2
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What Socratic holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.