Evidence map›Paper›PMID 39940297›Full record

Trial reportNutrients2025

Effects of Frozen Red Dragon Fruit Consumption on Metabolic Markers in Healthy Subjects and Individuals at Risk of Type 2 Diabetes.

Mildred Inna Marcela Flores-Verastegui, Shelly Coe, Jonathan Tammam, Haythim Almahjoubi, Robyn Bridle, Sabina Bi, Pariyarath Sangeetha Thondre

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05199636 (Effect of Dragon Fruit Consumption on Glycaemic Response and Blood Pressure in Individuals at Risk of Type 2 Diabetes), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05199636 nacompletednot on this map

Effect of Dragon Fruit Consumption on Glycaemic Response and Blood Pressure in Individuals at Risk of Type 2 Diabetes

TypeinterventionalSponsorOxford Brookes UniversityRan2022 to 2023Enrolled20ConditionsBlood Pressure, Glucose IntoleranceArmsDragon fruit product
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mildred Inna Marcela Flores-VerasteguiOxford Brookes Centre for Nutrition and Health, School of Sport, Nutrition and Allied Health Professions, Oxford Brookes University, Oxford OX3 0BP, UK.
Shelly CoeOxford Brookes Centre for Nutrition and Health, School of Sport, Nutrition and Allied Health Professions, Oxford Brookes University, Oxford OX3 0BP, UK.ORCID 0000-0003-0508-7507
Jonathan TammamOxford Brookes Centre for Nutrition and Health, School of Sport, Nutrition and Allied Health Professions, Oxford Brookes University, Oxford OX3 0BP, UK.ORCID 0000-0002-1790-5397
Haythim AlmahjoubiOxford Brookes Centre for Nutrition and Health, School of Sport, Nutrition and Allied Health Professions, Oxford Brookes University, Oxford OX3 0BP, UK.
Robyn BridleOxford Brookes Centre for Nutrition and Health, School of Sport, Nutrition and Allied Health Professions, Oxford Brookes University, Oxford OX3 0BP, UK.
Sabina BiOxford Brookes Centre for Nutrition and Health, School of Sport, Nutrition and Allied Health Professions, Oxford Brookes University, Oxford OX3 0BP, UK.
Pariyarath Sangeetha ThondreOxford Brookes Centre for Nutrition and Health, School of Sport, Nutrition and Allied Health Professions, Oxford Brookes University, Oxford OX3 0BP, UK.ORCID 0000-0003-2065-8443

Funding

PRODEP Mexico 511-6/18-7113
6 · The paper itself

Abstract

BACKGROUND/

objectivesThe interest in creating new products to decrease the risk of developing non-communicable chronic diseases such as type 2 diabetes (T2D) is increasing. These products include traditional food sources used as part of diverse cultures around the world, such as dragon fruit. The aim of this study was to investigate the effects of a frozen red dragon fruit (FRDF) beverage on blood pressure, glycaemic response (GR) and insulinaemic response (IR), lipid profile (LP), total antioxidant status (TAS), and C-reactive protein (CRP) levels in healthy subjects and individuals at risk of T2D.

methodsA parallel design trial (UREC registration number 211527; ClinicalTrials.gov registration number NCT05199636/19 January 2022) lasting four weeks and involving three testing sessions was conducted; participants were randomly assigned to one of two treatments (following general health guidance or consuming FRDF beverage). Systolic and diastolic blood pressures were taken; venous blood samples were collected to determine the LP and CRP levels; and capillary blood samples were taken before and after consuming a standard glucose drink to evaluate GR and IR at 15 min intervals (first hour) and 30 min intervals (second hour).

resultsEighteen participants completed this study, nine healthy (28.44 ± 5.20 years) and nine at risk (31.78 ± 12.11 years). The daily consumption of an FRDF-based beverage for four weeks by individuals at risk of T2D resulted in a reduction in blood pressure and IR-incremental area under the curve. The LP showed a downward trend, and a significant difference between treatments (

conclusionsBeverages based on FRDF may have the potential to decrease the risk of T2D.

Indexed as

Diabetes Mellitus, Type 2FruitAdultAntioxidantsBiomarkersBlood GlucoseBlood PressureCactaceaeC-Reactive ProteinFemaleHealthy VolunteersHumansInsulinLipidsMaleMiddle AgedAntioxidantsBiomarkersBlood GlucoseC-Reactive ProteinInsulinLipidsblood glucoseblood pressureglycaemic responseinsulinaemic responsered dragon fruit

Identifiers

PMID39940297
PMCPMC11821054

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.