Evidence map›Paper›PMID 39940458›Full record

ArticleNutrients2025

Association of Antioxidant Diet with Risk of Hyperemesis Gravidarum Among Chinese Pregnant Women: A Population-Based Cross-Sectional Study.

Lan Zhang, Xiang Li, Yuan Jin, Wenjie Cheng, Xinyu Zhang, Qian Ma, Aohua Liu, Siyang Chen, Yahui Fan, Shunming Zhang and 2 more

Abstract read
In one paragraph

Article in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Lan ZhangSchool of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an 710061, China.
Xiang LiSchool of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an 710061, China.
Yuan JinSchool of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an 710061, China.
Wenjie ChengSchool of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an 710061, China.
Xinyu ZhangSchool of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an 710061, China.
Qian MaSchool of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an 710061, China.
Aohua LiuSchool of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an 710061, China.
Siyang ChenSchool of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an 710061, China.
Yahui FanSchool of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an 710061, China.
Shunming ZhangSchool of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an 710061, China.
Jing LinSchool of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an 710061, China.
Le MaSchool of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an 710061, China.ORCID 0000-0001-7592-9779

Funding

Natural Science Foundation of Shaanxi Province 2023-JC-QN-0895Science Research on Chronic Disease Prevention in Children 202208159Young Elite Scientists Sponsorship Program by CAST 2023QNRC001
6 · The paper itself

Abstract

(1) Background: Oxidative stress plays a pivotal role in the pathophysiologic of hyperemesis gravidarum (HG). Epidemiological studies have explored the associations of specific antioxidant foods and nutrients with HG. However, evidence regarding the relationship between an antioxidant-rich diet and the risk of HG remains limited. The objective of this research was to explore the relationship between antioxidant-rich diet and HG. (2) Methods: This was a population-based cross-sectional study. A total of 2980 pregnant women were included in our population. A composite dietary antioxidant index (CDAI) was calculated by summing the standardized intakes of vitamins A, C, and E, selenium, zinc, and total carotene. A dietary antioxidant potential score (DAPS) was derived using reduced rank regression. Binary logistic regression models were employed to analyze the associations of CDAI and DAPS with risk of HG. (3) Results: In total, 241 (8.09%) cases of HG were identified in this study. After adjusting for potential confounders, including age, socioeconomic status, ethnicity, physical activity, current smoking status, current alcohol consumption, pre-pregnancy body mass index, nutritional supplement usage, total energy intake, gestational week, menstruation regularity, family history of HG, primigravida status, and quality of life during pregnancy, ORs (95% CIs) of HG in the highest tertiles were 0.31 (0.21-0.47) for CDAI and 0.41 (0.28-0.57) for DAPS when comparing lowest tertiles (all

Indexed as

AntioxidantsDietHyperemesis GravidarumAdultChinaCross-Sectional StudiesEast Asian PeopleFemaleHumansPregnancyRisk FactorsYoung AdultAntioxidantscomposite dietary antioxidant indexdietary antioxidant potential scorehyperemesis gravidarumoxidative stressreduced rank regression

Identifiers

PMID39940458
PMCPMC11820325

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.