Evidence map›Paper›PMID 39941020›Full record

ReviewInternational journal of molecular sciences2025

Nanotechnology Meets Phytotherapy: A Cutting-Edge Approach to Treat Bacterial Infections.

Katarzyna Pacyga, Paweł Pacyga, Emilia Szuba, Szymon Viscardi, Ewa Topola, Anna Duda-Madej

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Katarzyna PacygaDepartment of Environment Hygiene and Animal Welfare, Faculty of Biology and Animal Science, Wroclaw University of Environmental and Life Sciences, 50-375 Wroclaw, Poland.ORCID 0000-0002-5981-2914
Paweł PacygaDepartment of Thermodynamics and Renewable Energy Sources, Faculty of Mechanical and Power Engineering, Wrocław University of Science and Technology, 50-370 Wrocław, Poland.ORCID 0000-0002-2950-9308
Emilia SzubaFaculty of Biology and Animal Science, Wroclaw University of Environmental and Life Sciences, 50-375 Wroclaw, Poland.
Szymon ViscardiFaculty of Medicine, Wroclaw Medical University, Ludwika Pasteura 1, 50-367 Wrocław, Poland.ORCID 0009-0007-3668-6891
Ewa TopolaFaculty of Medicine, Wroclaw Medical University, Ludwika Pasteura 1, 50-367 Wrocław, Poland.ORCID 0000-0001-6409-7006
Anna Duda-MadejDepartment of Microbiology, Faculty of Medicine, Wroclaw Medical University, Chałubińskiego 4, 50-368 Wrocław, Poland.ORCID 0000-0001-8559-1695

Funding

This work was supported by the Wrocław University of Environmental and Life Sciences (Poland) as part of the research project entitled "Analysis of the effects of combinations of plant bioactive compounds, antibiotics, and nanoparticles in an in vitro mod N060/0010/23
6 · The paper itself

Abstract

The increasing prevalence of bacterial infections and the rise in antibiotic resistance have prompted the search for alternative therapeutic strategies. One promising approach involves combining plant-based bioactive substances with nanoparticles, which have demonstrated improved antimicrobial activity compared to their free forms, both in vitro, in vivo, and in clinical studies. This approach not only improves their stability but also enables targeted delivery to bacterial cells, reducing side effects and minimising the risk of resistance development, leading to more effective treatments. This narrative review explores the benefits of combining bioactive plant compounds (berberine, catechin, chelerythrine, cinnamaldehyde, ellagic acid, proanthocyanidin, and sanguinarine) with nanoparticles for the treatment of bacterial infections (caused by

Indexed as

Anti-Bacterial AgentsBacterial InfectionsNanotechnologyPhytotherapyAnimalsBacteriaHumansNanoparticlesAnti-Bacterial Agentsantibacterial activitybioactive compoundsbiological activitydrug-resistant bacteriananoparticles

Identifiers

PMID39941020
PMCPMC11818366

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.