Evidence mapPaperPMID 39941513Full record

ReviewJournal of clinical medicine2025

Home Enzyme Replacement Therapy in Gaucher Disease: A Review.

Beata Kieć-Wilk, Paul Guijt, Michaela Dan, Magy Abdelwahab, Shoshana Revel-Vilk, Christine Serratrice, International Gaucher Alliance (IGA) and the International Working Group on Gaucher Disease (IWGGD)

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Observational
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Beata Kieć-WilkUnit of Rare Metabolic Diseases, Department of Pathophysiology, Jagiellonian University Medical College, 31-121 Krakow, Poland.ORCID 0000-0002-2526-9714
Paul GuijtInternational Gaucher Alliance, London EC2A 4NE, UK.ORCID 0000-0002-2316-4564
Michaela DanRomanian Gaucher Association, 400540 Cluj-Napoca, Romania.ORCID 0009-0009-8255-4552
Magy AbdelwahabCairo University Pediatric Hospital Pediatric Hematology and BMT Department and Gaucher Disease Clinic, Kasr Elainy Hospital, Cairo 11562, Egypt.
Shoshana Revel-VilkGaucher Unit, The Eisenberg R&D Authority, Shaare Zedek Medical Center, Jerusalem 9103102, Israel.ORCID 0000-0001-9151-0337
Christine SerratriceDivision of Internal Medicine for the Aged, University Hospital of Geneva, Thônex, 1256 Geneva, Switzerland.ORCID 0000-0001-9940-4686
International Gaucher Alliance (IGA) and the International Working Group on Gaucher Disease (IWGGD)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since the early 1990s, Gaucher Disease has been a pioneering condition for home-based enzyme replacement therapy (ERT), marking a significant shift in patient care. Since then, many countries have adopted this approach. However, home ERT is not possible in all countries.

Indexed as

complianceenzyme replacement therapyGaucher diseasehome therapysafety

Identifiers

PMID39941513
PMCPMC11818897

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.