Evidence map›Paper›PMID 39943547›Full record

ArticleSensors (Basel, Switzerland)2025

Relationship Between Signals from Cerebral near Infrared Spectroscopy Sensor Technology and Objectively Measured Cerebral Blood Volume: A Systematic Scoping Review.

Noah Silvaggio, Kevin Y Stein, Amanjyot Singh Sainbhi, Nuray Vakitbilir, Tobias Bergmann, Abrar Islam, Rakibul Hasan, Mansoor Hayat, Frederick A Zeiler

Abstract readScoping Review
PubMed Full text at PMC Publisher
In one paragraph

Article in Sensors (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Noah SilvaggioDepartment of Human Anatomy and Cell Science, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB R3T 2N2, Canada.ORCID 0009-0003-3860-8134
Kevin Y SteinDepartment of Biomedical Engineering, Price Faculty of Engineering, University of Manitoba, Winnipeg, MB R3T 2N2, Canada.ORCID 0000-0002-5983-008X
Amanjyot Singh SainbhiDepartment of Biomedical Engineering, Price Faculty of Engineering, University of Manitoba, Winnipeg, MB R3T 2N2, Canada.ORCID 0000-0003-3231-5683
Nuray VakitbilirDepartment of Biomedical Engineering, Price Faculty of Engineering, University of Manitoba, Winnipeg, MB R3T 2N2, Canada.ORCID 0000-0003-2764-145X
Tobias BergmannDepartment of Biomedical Engineering, Price Faculty of Engineering, University of Manitoba, Winnipeg, MB R3T 2N2, Canada.
Abrar IslamDepartment of Biomedical Engineering, Price Faculty of Engineering, University of Manitoba, Winnipeg, MB R3T 2N2, Canada.ORCID 0009-0006-6669-3374
Rakibul HasanDepartment of Biomedical Engineering, Price Faculty of Engineering, University of Manitoba, Winnipeg, MB R3T 2N2, Canada.
Mansoor HayatSection of Neurosurgery, Department of Surgery, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB R3T 2N2, Canada.ORCID 0000-0002-1131-2398
Frederick A ZeilerDepartment of Biomedical Engineering, Price Faculty of Engineering, University of Manitoba, Winnipeg, MB R3T 2N2, Canada.ORCID 0000-0003-1737-0510

Funding

Canada Foundation for Innovation 38583CIHR N/AHealth Sciences Centre Foundation Winnipeg N/AMPI Neuroscience Research Operating Fund N/ANatural Sciences and Engineering Research Council of Canada ALLRP-576386-22Natural Sciences and Engineering Research Council of Canada ALLRP-578524-22Natural Sciences and Engineering Research Council of Canada ALLRP 586244-23Natural Sciences and Engineering Research Council of Canada ALLRP-590680-2023Natural Sciences and Engineering Research Council of Canada ALLRP 597442-24Natural Sciences and Engineering Research Council of Canada ALLRP-597708-24Natural Sciences and Engineering Research Council of Canada DGECR-2022-00260Natural Sciences and Engineering Research Council of Canada I2IPJ 586104-23Natural Sciences and Engineering Research Council of Canada RGPIN-2022-03621Natural Sciences and Engineering Research Council of Canada CGS-D program CGS D-579021-2023Natural Sciences and Engineering Research Council of Canada CGS-M program N/APan Am Clinic Foundation of Winnipeg N/AResearch Manitoba 3906Research Manitoba 5429Research Manitoba 5914University of Manitoba Endowed Manitoba Public Insurance (MPI) Chair in Neuroscience N/AUniversity of Manitoba Graduate Enhancement of Tri-Agency Stipends (GETS) program N/AUniversity of Manitoba Graduate Fellowship - Biomedical Engineering N/AUniversity of Manitoba Graduate Fellowship - Human Anatomy and Cell Sciences N/AUniversity of Manitoba MD/PhD program N/AUniversity of Manitoba R.G. and E.M. Graduate Fellowship (Doctoral) in Biomedical Engineering N/A
6 · The paper itself

Abstract

Cerebral blood volume (CBV) is an essential metric that indicates and evaluates various healthy and pathologic conditions. Most methods of CBV measurement are cumbersome and have a poor temporal resolution. Recently, it has been proposed that signals and derived metrics from cerebral near-infrared spectroscopy (NIRS), a non-invasive sensor, can be used to estimate CBV. However, this association remains vastly unexplored. As such, this scoping review aimed to examine the literature on the relationship between cerebral NIRS signals and CBV. A search of six databases was conducted conforming to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines to assess the following search question: What are the associations between various NIRS cerebral signals and CBV? The database search yielded 3350 unique results. Seven of these articles were included in this review based on the inclusion and exclusion criteria. An additional study was identified and included while examining the articles' reference sections. Overall, the literature for this systematic scoping review shows extreme variation in the association between cerebral NIRS signals and CBV, with few sources objectively documenting a true statistical association between the two. This review highlights the current critical knowledge gap and emphasizes the need for further research in the area.

Indexed as

BrainCerebral Blood VolumeCerebrovascular CirculationHumansSpectroscopy, Near-InfraredCBVcerebral blood volumecerebral near-infrared spectroscopyNIRS

Identifiers

PMID39943547
PMCPMC11819900

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.