Evidence map›Paper›PMID 39944348›Full record

ArticleHeliyon2025

The effects of

Temidayo S Omolaoye, Surendra Singh Rawat, Naglaa Gamil Shehab, Eslam El Nebrisi, Stefan S Du Plessis

Abstract read
In one paragraph

Article in Heliyon, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Temidayo S OmolaoyeCollege of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai Health, DHCC, P.O.Box 505055, Dubai, United Arab Emirates.
Surendra Singh RawatResearch and Graduate Studies, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai Health, Dubai, United Arab Emirates.
Naglaa Gamil ShehabPharmaceutical Sciences Department, College of Pharmacy, Dubai Medical University, Dubai, 19099, United Arab Emirates.
Eslam El NebrisiDepartment of Biomedical Sciences, Dubai Medical College for Girls, Dubai Medical University, Dubai, 20170, United Arab Emirates.
Stefan S Du PlessisCollege of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai Health, DHCC, P.O.Box 505055, Dubai, United Arab Emirates.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective and rationale: Although monosodium glutamate (MSG), commonly used to enrich food flavour, is generally considered safe for consumption, evidence has shown its adverse effects on physiological functions, including male reproduction, when consumed excessively. Methods: Eighteen male Wistar rats were randomly divided into three groups. Animals were orally (oral gavage) administered MSG (900 mg/kg/day for 45days), MSG and Maca (900 mg/kg/day of MSG and 500 mg/kg/day of black Results: MSG administration significantly reduced total and progressive sperm motility ( Conclusion: Findings highlights how MSG could cause male reproductive dysfunction via reduction of TAC, increase in pro-inflammatory cytokines, alter reproductive hormones and reduced protein expression of steroidogenic markers. Treatment with Maca significantly improved sperm motility, possibly by enhancing TAC levels and reducing proinflammatory cytokines. However, this hypothesis needs further investigation.

Indexed as

InflammationLepidium meyeniiMacaMale subfertilityMonosodium glutamateOxidative stressSteroidogenesis

Identifiers

PMID39944348
PMCPMC11815890

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.