ArticleAnnals of cardiothoracic surgery2025
A critical evaluation of donor heart offer acceptance in the United Kingdom.
Article in Annals of cardiothoracic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Ex situ heart perfusion: a novel model for drug validation and translation.Frontiers in cardiovascular medicine · 2026Article
- Article
- Gap between availability and utilization of cardiac donors: analysis of determining factors in Ecuador.Archivos peruanos de cardiologia y cirugia cardiovascularArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: In the United Kingdom (UK), the adoption of donation after circulatory determination of death (DCD) has boosted transplantation rates by 20%. However, about 100 patients per year on the waitlist still do not receive a transplant due to low transplantation rates. Current reports review rates of utilisation after offer acceptance but fail to report the offer acceptance rate and the reasons for offer declines. We have therefore analysed the reasons why heart offers were declined over the past 16 years. Methods: A retrospective analysis was conducted on the primary reasons for the decline of heart offers between 1 Results: During this period, 2,673 heart offers were accepted for transplantation. Comparatively, 6,310 offers were declined, most commonly due to poor function (35.8%) and 'donor past medical history (PMH)' (20.4%), together accounting for 56% of all declined heart offers. The largest category was 'organ-related' reasons (47.6%), and the smallest group was 'logistical' reasons (1.0%). Recipient-related factors accounted for only 7.8% of declined offers. Conclusions: Donor heart function and PMH are the most common reasons for declining heart offers, with non-clinical factors also contributing to offer declines. Greater acceptance rates can be achieved with greater logistical support for the UK heart transplantation networks and the implementation of more robust and objective assessment methods for offered hearts, including biomarkers and coronary angiography, particularly in DCD donation.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.