Evidence map›Paper›PMID 39945861›Full record

ReviewPediatric nephrology (Berlin, Germany)2025

Next-generation nephrology: part 1-an aid for genetic and genomic testing in pediatric nephrology.

Asheeta Gupta, Kushani Jayasinghe, Amar Majmundar, Nina Mann, Rajiv Sinha, Matthew G Sampson, Catherine Quinlan

Abstract readReview
In one paragraph

Review in Pediatric nephrology (Berlin, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Asheeta GuptaDept of Pediatric Nephrology, Great Ormond Street Hospital for Children, NHS Foundation Trust, London, UK. asheeta.gupta@gosh.nhs.uk.ORCID 0000-0002-9654-6192
Kushani JayasingheKidney Regeneration, Murdoch Research Institute, Melbourne, Australia.
Amar MajmundarDivision of Pediatric Nephrology, Boston Children's Hospital, Boston, MA, USA.
Nina MannDivision of Pediatric Nephrology, Boston Children's Hospital, Boston, MA, USA.
Rajiv SinhaInstitute of Child Health, Kolkata, India.
Matthew G SampsonDivision of Pediatric Nephrology, Boston Children's Hospital, Boston, MA, USA.
Catherine QuinlanDept of Paediatric Nephrology, Royal Children's Hospital, Melbourne, Australia.

Funding

Delineation of pathogenic mechanisms of NOS1AP and TRIM8 mutations in monogenic SRNS/FSGS.K08DK125768 · NIDDK · BOSTON CHILDREN'S HOSPITAL · PI MAJMUNDAR, AMAR J · 2021 to 2025
$841k
NIDDK NIH HHS K08 DK125768
6 · The paper itself

Abstract

Genetic and genomic testing has transformed the practice of clinical nephrology. Yet nephrologists have identified genetic literacy and access to kidney genetic care models as critical barriers to utilising this technology in their practice. To accelerate the implementation of genomic medicine in clinical nephrology, we provide a two-part evidence-based educational review. This inaugural segment highlights the importance of genomic testing for kidney disease and the steps a nephrologist can take to understand and apply this technology to one's own clinical practice. The second part delineates approaches to operationalising a kidney genetics service based on existing models, reported barriers, and the authors' experiences in developing kidney clinic models for different settings.

Indexed as

Genetic TestingGenomicsKidney DiseasesNephrologyPediatricsChildHumansChronic kidney diseaseGeneticsGenomicsUtility

Identifiers

PMID39945861
PMCPMC12297000

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.