ArticleProceedings of the National Academy of Sciences of the United States of America2025
Identification of a protective antigen reveals the trade-off between iron acquisition and antigen exposure in a global fungal pathogen.
Yeqi Li, Tuyetnhu Pham, Kenton Hipsher, Christopher W J Lee, Jie Jiao, Josef M Penninger, James W Kronstad, Yumeng Fan, Youbao Zhao, Suresh Ambati and 3 more
Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
13 authors.
Yeqi LiDepartment of Microbiology, University of Georgia, Athens, GA 30602.
Tuyetnhu PhamDepartment of Plant Biology, University of Georgia, Athens, GA 30602.
Kenton HipsherDepartment of Microbiology, University of Georgia, Athens, GA 30602.
Christopher W J LeeMichael Smith Laboratories, Department of Microbiology and Immunology, University of British Columbia, Vancouver, BC V6T 1Z4, Canada.
Jie JiaoDepartment of Medical Genetics, Life Sciences Institute, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.ORCID 0009-0009-7781-5762
Josef M PenningerDepartment of Medical Genetics, Life Sciences Institute, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.
James W KronstadMichael Smith Laboratories, Department of Microbiology and Immunology, University of British Columbia, Vancouver, BC V6T 1Z4, Canada.ORCID 0000-0003-4240-6976
Yumeng FanDepartment of Microbiology, University of Georgia, Athens, GA 30602.ORCID 0000-0003-4975-3751
Youbao ZhaoDepartment of Microbiology, University of Georgia, Athens, GA 30602.
Suresh AmbatiDepartment of Genetics, University of Georgia, Athens, GA 30602.
Richard B MeagherDepartment of Genetics, University of Georgia, Athens, GA 30602.
Xiaofeng XieDepartment of Microbiology, University of Georgia, Athens, GA 30602.
Xiaorong LinDepartment of Microbiology, University of Georgia, Athens, GA 30602.ORCID 0000-0002-3390-8387
Funding
Comparative and functional genomics of C. neoformansR01AI053721 · NIAID · UNIVERSITY OF BRITISH COLUMBIA · PI KRONSTAD, JAMES W · 2003 to 2024
$5.4M
Defining the genetic network governing cryptococcal morphological transitionR01AI140719 · NIAID · UNIVERSITY OF GEORGIA · PI Xiaorong Lin · 2018 to 2026
$4.1M
Systematic investigation of GPI-anchored mannoproteins in Cryptococcus neoformansR21AI150641 · NIAID · UNIVERSITY OF GEORGIA · PI LIN, XIAORONG · 2020 to 2021
$415k
Develop and Assess mRNA Lipid Nanoparticle Vaccines Against CryptococcosisR21AI170106 · NIAID · UNIVERSITY OF GEORGIA · PI LIN, XIAORONG, MEAGHER, RICHARD BRIAN · 2023 to 2024
$384k
HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) R01AI053721HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) R01AI140719HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) R21AI150641HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) R21AI170106NIAID NIH HHS R01 AI053721NIAID NIH HHS R01 AI140719NIAID NIH HHS R21 AI150641NIAID NIH HHS R21 AI170106
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.
Identification of a protective antigen reveals the trade-off between iron acquisition and antigen exposure in a global fungal pathogen. · full record | Socratic